Isotianil

Cat. No.: HY-W075256 Purity: 98.13%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Isotianil is a plant defense inducer that has no direct antimicrobial effect but instead activates typical plant defense responses. Isotianil can be used as a plant protection agent for controlling rice blast.

For research use only. We do not sell to patients.

Isotianil Chemical Structure

CAS No. : 224049-04-1

Size	Price	Stock	Quantity
25 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 95	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Description

In Vitro

Isotianil (0.1-100 ppm, 2 days) can induce the accumulation of endogenous plant resistance-related enzymes such as lipoxygenase, phenylalanine ammonia lyase and chitinase in rice tissues. Induction of disease resistance-related genes, including WRKY45^[1].
Isotianil has a good preventive effect on leaf blast at a lower dose, and has shown plant resistance induction against various bacterial diseases, including bacterial seedling rot caused by Burkholderia^[1].
Isotianil effectively protects seedling wheat plants against the virulent MoT isolate BR32, preventing the invasive growth of MoT from progressing from the initially attacked epidermal cells to the mesophyll^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

298.15

Formula

C₁₁H₅Cl₂N₃OS

CAS No.

224049-04-1

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C1=C(Cl)C(Cl)=NS1)NC2=CC=CC=C2C#N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

RT, protect from light

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 87.5 mg/mL (293.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3540 mL	16.7701 mL	33.5402 mL
5 mM	0.6708 mL	3.3540 mL	6.7080 mL
10 mM	0.3354 mL	1.6770 mL	3.3540 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.13%

Select Batch:

Data Sheet (274 KB) SDS (392 KB)

COA (252 KB) HNMR (243 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Ogawa M, Kadowaki A, Yamada T, et al. Applied development of a novel fungicide isotianil (STOUT)[J]. Sumitomo Kagaku, 2011, 1: 1-15.

[2]. Katharina Portz, et al. Wheat blast caused by Magnaporthe oryzae pathovar Triticum is efficiently controlled by the plant defence inducer isotianil. Journal of Plant Diseases and Protection volume 128, pages249-259 (2021).

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.3540 mL	16.7701 mL	33.5402 mL	83.8504 mL
	5 mM	0.6708 mL	3.3540 mL	6.7080 mL	16.7701 mL
	10 mM	0.3354 mL	1.6770 mL	3.3540 mL	8.3850 mL
	15 mM	0.2236 mL	1.1180 mL	2.2360 mL	5.5900 mL
	20 mM	0.1677 mL	0.8385 mL	1.6770 mL	4.1925 mL
	25 mM	0.1342 mL	0.6708 mL	1.3416 mL	3.3540 mL
	30 mM	0.1118 mL	0.5590 mL	1.1180 mL	2.7950 mL
	40 mM	0.0839 mL	0.4193 mL	0.8385 mL	2.0963 mL
	50 mM	0.0671 mL	0.3354 mL	0.6708 mL	1.6770 mL
	60 mM	0.0559 mL	0.2795 mL	0.5590 mL	1.3975 mL
	80 mM	0.0419 mL	0.2096 mL	0.4193 mL	1.0481 mL
	100 mM	0.0335 mL	0.1677 mL	0.3354 mL	0.8385 mL

Isotianil Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isotianil224049-04-1Bacterialplant defenseplant protectionrice blastInhibitorinhibitorinhibit

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