2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. Isotodesnitazene

Isotodesnitazene is a kind of opioids. Isotodesnitazene primarily acts on μ-opioid receptors (MOR). Isotodesnitazene has an EC50 of 34.8 nM for MOR-βarr2 and 142 nM for MOR-mini-Gi. Isotodesnitazene can be used in the study of opioids.

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Isotodesnitazene Chemical Structure

Isotodesnitazene Chemical Structure

CAS No. : 2732926-27-9

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Based on 1 publication(s) in Google Scholar

Isotodesnitazene Related Antibodies

Top Publications Citing Use of Products

View All Opioid Receptor Isoform Specific Products:

View All Isoforms
μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

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Description

Isotodesnitazene is a kind of opioids. Isotodesnitazene primarily acts on μ-opioid receptors (MOR). Isotodesnitazene has an EC50 of 34.8 nM for MOR-βarr2 and 142 nM for MOR-mini-Gi. Isotodesnitazene can be used in the study of opioids[1].

IC50 & Target

μ Opioid Receptor/MOR

 

Molecular Weight

365.51

Formula

C23H31N3O
CAS No.
Appearance

Oil

Color

White to off-white

SMILES

CC(C)OC(C=C1)=CC=C1CC2=NC3=C(N2CCN(CC)CC)C=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (273.59 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7359 mL 13.6795 mL 27.3590 mL
5 mM 0.5472 mL 2.7359 mL 5.4718 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7359 mL 13.6795 mL 27.3590 mL 68.3976 mL
5 mM 0.5472 mL 2.7359 mL 5.4718 mL 13.6795 mL
10 mM 0.2736 mL 1.3680 mL 2.7359 mL 6.8398 mL
15 mM 0.1824 mL 0.9120 mL 1.8239 mL 4.5598 mL
20 mM 0.1368 mL 0.6840 mL 1.3680 mL 3.4199 mL
25 mM 0.1094 mL 0.5472 mL 1.0944 mL 2.7359 mL
30 mM 0.0912 mL 0.4560 mL 0.9120 mL 2.2799 mL
40 mM 0.0684 mL 0.3420 mL 0.6840 mL 1.7099 mL
50 mM 0.0547 mL 0.2736 mL 0.5472 mL 1.3680 mL
60 mM 0.0456 mL 0.2280 mL 0.4560 mL 1.1400 mL
80 mM 0.0342 mL 0.1710 mL 0.3420 mL 0.8550 mL
100 mM 0.0274 mL 0.1368 mL 0.2736 mL 0.6840 mL
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Isotodesnitazene Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isotodesnitazene2732926-27-9Opioid ReceptorInhibitorinhibitorinhibit

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