2. Protein Tyrosine Kinase/RTK
  3. Itk
  4. ITK inhibitor 2

ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor extracted from patent WO2011065402A1, compound 4, with an IC50 of 2 nM.

For research use only. We do not sell to patients.

ITK inhibitor 2 Chemical Structure

ITK inhibitor 2 Chemical Structure

CAS No. : 1309784-09-5

Size Price Stock Quantity
5 mg USD 150 In-stock
10 mg USD 250 In-stock
25 mg USD 550 In-stock
50 mg USD 950 In-stock
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Based on 1 publication(s) in Google Scholar

ITK inhibitor 2 Related Antibodies

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Description

ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor extracted from patent WO2011065402A1, compound 4, with an IC50 of 2 nM.

IC50 & Target

IC50: 2 nM (ITK inhibitor 2)[1]
Molecular Weight

435.56

Formula

C25H33N5O2
CAS No.
Appearance

Solid

Color

Gray to brown

SMILES

CC1(CC2=C(C(C3=CC4=CC=C(N(C)C([C@@H](N5CCOCC5)C)=O)C=C4N3)=NN2)CC1)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (286.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2959 mL 11.4795 mL 22.9590 mL
5 mM 0.4592 mL 2.2959 mL 4.5918 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2959 mL 11.4795 mL 22.9589 mL 57.3974 mL
5 mM 0.4592 mL 2.2959 mL 4.5918 mL 11.4795 mL
10 mM 0.2296 mL 1.1479 mL 2.2959 mL 5.7397 mL
15 mM 0.1531 mL 0.7653 mL 1.5306 mL 3.8265 mL
20 mM 0.1148 mL 0.5740 mL 1.1479 mL 2.8699 mL
25 mM 0.0918 mL 0.4592 mL 0.9184 mL 2.2959 mL
30 mM 0.0765 mL 0.3826 mL 0.7653 mL 1.9132 mL
40 mM 0.0574 mL 0.2870 mL 0.5740 mL 1.4349 mL
50 mM 0.0459 mL 0.2296 mL 0.4592 mL 1.1479 mL
60 mM 0.0383 mL 0.1913 mL 0.3826 mL 0.9566 mL
80 mM 0.0287 mL 0.1435 mL 0.2870 mL 0.7175 mL
100 mM 0.0230 mL 0.1148 mL 0.2296 mL 0.5740 mL
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ITK inhibitor 2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ITK inhibitor 21309784-09-5ITK inhibitor2ITK inhibitor-2ItkInterleukin-2 inducible T-cell kinaseIL2 inducible T-cell kinaseInhibitorinhibitorinhibit

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