2. Neuronal Signaling
  3. Dopamine Transporter Monoamine Oxidase
  4. J147

J147 is an exceptionally potent, orally active, neuroprotective agent for cognitive enhancement. J147 can pass the blood brain barrier (BBB). J147 can inhibit monoamine oxidase B (MAO B) and the dopamine transporter. J147 plays an impotant role in Alzheimer’s disease (AD).

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J147 Chemical Structure

J147 Chemical Structure

CAS No. : 1807913-16-1

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Based on 1 publication(s) in Google Scholar

Other Forms of J147:

J147 Related Antibodies

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MAO-A MAO-B

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Description

J147 is an exceptionally potent, orally active, neuroprotective agent for cognitive enhancement. J147 can pass the blood brain barrier (BBB). J147 can inhibit monoamine oxidase B (MAO B) and the dopamine transporter. J147 plays an impotant role in Alzheimer’s disease (AD)[1].

Molecular Weight

350.33

Formula

C18H17F3N2O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC1=CC=CC(/C=N/N(C2=C(C=C(C=C2)C)C)C(C(F)(F)F)=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.90%

SDS (251 KB)

COA (248 KB)

Handling Instructions (2659 KB)
References
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J147 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

J1471807913-16-1J 147J-147Dopamine TransporterMonoamine OxidaseDATSLC6A3MAOBBBmonoamineoxidaseMAO BdopamineAlzheimer? diseaseneuroprotectiveInhibitorinhibitorinhibit

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