2. Neuronal Signaling
  3. Dopamine Transporter
  4. JJC8-088 dioxalate

JJC8-088 dioxalate is the dioxalate salt form of JJC8-088 (HY-158013). JJC8-088 dioxalate is a derivative of modafinil. JJC8-088 dioxalate is an inhibitor for dopamine transporter (DAT). JJC8-088 dioxalate exhibits behavioral characteristics similar to cocaine in rat models, and can be to study psychostimulant use disorders.

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JJC8-088 dioxalate Chemical Structure

JJC8-088 dioxalate Chemical Structure

CAS No. : 2068692-71-5

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Other Forms of JJC8-088 dioxalate:

JJC8-088 dioxalate Related Antibodies

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Description

JJC8-088 dioxalate is the dioxalate salt form of JJC8-088 (HY-158013). JJC8-088 dioxalate is a derivative of modafinil. JJC8-088 dioxalate is an inhibitor for dopamine transporter (DAT). JJC8-088 dioxalate exhibits behavioral characteristics similar to cocaine in rat models, and can be to study psychostimulant use disorders[1].

Molecular Weight

678.70

Formula

C32H36F2N2O10S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C(C1=CC=C(C=C1)F)C2=CC=C(C=C2)F)CCN3CCN(CC3)CC(CC4=CC=CC=C4)O.O=C(O)C(O)=O.O=C(O)C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (49.11 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4734 mL 7.3670 mL 14.7340 mL
5 mM 0.2947 mL 1.4734 mL 2.9468 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4734 mL 7.3670 mL 14.7341 mL 36.8351 mL
5 mM 0.2947 mL 1.4734 mL 2.9468 mL 7.3670 mL
10 mM 0.1473 mL 0.7367 mL 1.4734 mL 3.6835 mL
15 mM 0.0982 mL 0.4911 mL 0.9823 mL 2.4557 mL
20 mM 0.0737 mL 0.3684 mL 0.7367 mL 1.8418 mL
25 mM 0.0589 mL 0.2947 mL 0.5894 mL 1.4734 mL
30 mM 0.0491 mL 0.2456 mL 0.4911 mL 1.2278 mL
40 mM 0.0368 mL 0.1842 mL 0.3684 mL 0.9209 mL
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JJC8-088 dioxalate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JJC8-088 dioxalate2068692-71-5Dopamine TransporterDATSLC6A3psychostimulantcocaineInhibitorinhibitorinhibit

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