1. Metabolic Enzyme/Protease Neuronal Signaling
  2. FAAH
  3. JNJ-40355003

JNJ-40355003 is a potent and selective atty acid amide hydrolase (FAAH) inhibitor.

For research use only. We do not sell to patients.

JNJ-40355003 Chemical Structure

JNJ-40355003 Chemical Structure

CAS No. : 1394894-41-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 297 In-stock
Solution
10 mM * 1 mL in DMSO USD 297 In-stock
Solid
5 mg USD 270 In-stock
10 mg USD 430 In-stock
25 mg USD 860 In-stock
50 mg USD 1380 In-stock
100 mg USD 2200 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

JNJ-40355003 is a potent and selective atty acid amide hydrolase (FAAH) inhibitor[1].

Molecular Weight

422.91

Formula

C23H23ClN4O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1CCN(CC2=CC(OC3=CC=C(Cl)C=C3)=CC=C2)CC1)NC4=CC=CN=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (295.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3646 mL 11.8228 mL 23.6457 mL
5 mM 0.4729 mL 2.3646 mL 4.7291 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3646 mL 11.8228 mL 23.6457 mL 59.1142 mL
5 mM 0.4729 mL 2.3646 mL 4.7291 mL 11.8228 mL
10 mM 0.2365 mL 1.1823 mL 2.3646 mL 5.9114 mL
15 mM 0.1576 mL 0.7882 mL 1.5764 mL 3.9409 mL
20 mM 0.1182 mL 0.5911 mL 1.1823 mL 2.9557 mL
25 mM 0.0946 mL 0.4729 mL 0.9458 mL 2.3646 mL
30 mM 0.0788 mL 0.3941 mL 0.7882 mL 1.9705 mL
40 mM 0.0591 mL 0.2956 mL 0.5911 mL 1.4779 mL
50 mM 0.0473 mL 0.2365 mL 0.4729 mL 1.1823 mL
60 mM 0.0394 mL 0.1970 mL 0.3941 mL 0.9852 mL
80 mM 0.0296 mL 0.1478 mL 0.2956 mL 0.7389 mL
100 mM 0.0236 mL 0.1182 mL 0.2365 mL 0.5911 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
JNJ-40355003
Cat. No.:
HY-18013
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