2. Metabolic Enzyme/Protease Neuronal Signaling
  3. Glucosidase Cholinesterase (ChE)
  4. Kaempferol-3,7-di-O-β-glucoside

Kaempferol-3,7-di-O-β-glucoside  (Synonyms: Kaempferol 3,7-diglucoside)

Cat. No.: HY-N8161
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Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside), a flavonol, possesses enzyme inhibition property towards α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3,7-di-O-β-glucoside protects differentiating neuronal cells, SH-SY5Y from Amyloid β peptide-induced injury. Kaempferol-3,7-di-O-β-glucoside has the potential for Alzheimer's research.

For research use only. We do not sell to patients.

Kaempferol-3,7-di-O-β-glucoside Chemical Structure

Kaempferol-3,7-di-O-β-glucoside Chemical Structure

CAS No. : 25615-14-9

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Based on 1 publication(s) in Google Scholar

Kaempferol-3,7-di-O-β-glucoside Related Antibodies

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Description

Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside), a flavonol, possesses enzyme inhibition property towards α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3,7-di-O-β-glucoside protects differentiating neuronal cells, SH-SY5Y from Amyloid β peptide-induced injury. Kaempferol-3,7-di-O-β-glucoside has the potential for Alzheimer's research[1].

Cellular Effect
Cell Line Type Value Description References
BV-2 IC50
28.89 μM
Compound: 16
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method
[PMID: 23149227]
In Vitro

Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside; 0.1, 100 μM) has effective inhibition in Aβ1-42 fibril formation. Kaempferol-3,7-di-O-β-glucoside has less neurotoxicity on the cultured SH-SY5Y cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Kaempferol-3,7-di-O-β-glucoside Related Antibodies
Molecular Weight

610.52

Formula

C27H30O16
CAS No.
SMILES

O=C1C(O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]([C@H]2O)CO)=C(C(C=C3)=CC=C3O)OC4=CC(O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]([C@H]5O)CO)=CC(O)=C14
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Kaempferol-3,7-di-O-β-glucoside Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kaempferol-3,7-di-O-β-glucoside25615-14-9Kaempferol 3,7-diglucosideGlucosidaseCholinesterase (ChE)α-amylaseα-glucosidaseAcetylcholinesteraseSH-SY5YAmyloid βAlzheimer'sInhibitorinhibitorinhibit

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