Kayexalate

Cat. No.: HY-148162: FAQs
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Kayexalate, a cation-exchange resin, is an orally active plasma potassium inhibitor. Kayexalate can be used in the research of hyperkalemia.

For research use only. We do not sell to patients.

Kayexalate Chemical Structure

CAS No. : 37349-16-9

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Description

Kayexalate, a cation-exchange resin, is an orally active plasma potassium inhibitor. Kayexalate can be used in the research of hyperkalemia^[1]^[2].

In Vivo

Propiomazine (5 g/kg, oral gavage) lowers serum Li concentrations in CD-1 mice^[2].
Propiomazine (5 g/kg, oral gavage) reduces serum K concentrations in CD-1 mice^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	CD-1 mice given with LiCl (125 mg/kg, i.v.)^[2]
Dosage:	5 g/kg
Administration:	Oral gavage, at 20, 40, 90, 150, and 210 minutes after LiCl challenge.
Result:	Effectively enhanced the elimination of intravenously administered Li.

CAS No.

37349-16-9

SMILES

[Kayexalate]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Harel Z, et al. Gastrointestinal adverse events with sodium polystyrene sulfonate (Kayexalate) use: a systematic review. Am J Med. 2013 Mar;126(3):264.e9-24. [Content Brief]

[2]. J G Linakis, et al. Enhancement of lithium elimination by multiple-dose sodium polystyrene sulfonate. Acad Emerg Med. 1997 Mar;4(3):175-8. [Content Brief]

[3]. Linakis JG, et al. Sodium polystyrene sulfonate treatment for lithium toxicity: effects on serum potassium concentrations. Acad Emerg Med. 1996 Apr;3(4):333-7. [Content Brief]

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kayexalate37349-16-9OthersHyperkalemiapotassiumLiserum KInhibitorinhibitorinhibit

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