KB-05

Cat. No.: HY-149461 Purity: 95.86%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

KB-05 is an electrophilic fragment molecule that can be used in DIA-based quantitative chemical proteomic screening studies.

For research use only. We do not sell to patients.

KB-05 Chemical Structure

CAS No. : 1956368-15-2

Size	Price	Stock	Quantity
5 mg	USD 230	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 370	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Description

KB-05 is an electrophilic fragment molecule that can be used in DIA-based quantitative chemical proteomic screening studies.

Molecular Weight

302.17

Formula

C₁₅H₁₂BrNO

CAS No.

1956368-15-2

Appearance

Solid

Color

White to yellow

SMILES

O=C(N(C1=CC=C(C=C1)Br)C2=CC=CC=C2)C=C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (330.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3094 mL	16.5470 mL	33.0940 mL
5 mM	0.6619 mL	3.3094 mL	6.6188 mL
10 mM	0.3309 mL	1.6547 mL	3.3094 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.86%

Select Batch:

Data Sheet (269 KB) SDS (615 KB)

COA (250 KB) HNMR (255 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Matthew Patricelli, et al. Compounds and methods for modulating immune-related proteins. WO2021076703. 2020-10-15

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.3094 mL	16.5470 mL	33.0940 mL	82.7349 mL
	5 mM	0.6619 mL	3.3094 mL	6.6188 mL	16.5470 mL
	10 mM	0.3309 mL	1.6547 mL	3.3094 mL	8.2735 mL
	15 mM	0.2206 mL	1.1031 mL	2.2063 mL	5.5157 mL
	20 mM	0.1655 mL	0.8273 mL	1.6547 mL	4.1367 mL
	25 mM	0.1324 mL	0.6619 mL	1.3238 mL	3.3094 mL
	30 mM	0.1103 mL	0.5516 mL	1.1031 mL	2.7578 mL
	40 mM	0.0827 mL	0.4137 mL	0.8273 mL	2.0684 mL
	50 mM	0.0662 mL	0.3309 mL	0.6619 mL	1.6547 mL
	60 mM	0.0552 mL	0.2758 mL	0.5516 mL	1.3789 mL
	80 mM	0.0414 mL	0.2068 mL	0.4137 mL	1.0342 mL
	100 mM	0.0331 mL	0.1655 mL	0.3309 mL	0.8273 mL

KB-05 Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KB-051956368-15-2KB05KB 05OthersElectrophilic fragmentsDIAproteomicsscreeningInhibitorinhibitorinhibit

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