2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. KCNK13-IN-1

KCNK13-IN-1 (example 71), a KCNK13 antagonist, is an anti-inflammatory agent, with an IC50 of <200 nM for IL-1 β.

For research use only. We do not sell to patients.

KCNK13-IN-1 Chemical Structure

KCNK13-IN-1 Chemical Structure

CAS No. : 361368-24-3

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KCNK13-IN-1 Related Antibodies

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Description

KCNK13-IN-1 (example 71), a KCNK13 antagonist, is an anti-inflammatory agent, with an IC50 of <200 nM for IL-1 β[1].

Molecular Weight

292.30

Formula

C15H12N6O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC1=NON=C1C2=NC3=CC=CC=C3N2CC4=CC=NC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 11.3 mg/mL (38.66 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4211 mL 17.1057 mL 34.2114 mL
5 mM 0.6842 mL 3.4211 mL 6.8423 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4211 mL 17.1057 mL 34.2114 mL 85.5286 mL
5 mM 0.6842 mL 3.4211 mL 6.8423 mL 17.1057 mL
10 mM 0.3421 mL 1.7106 mL 3.4211 mL 8.5529 mL
15 mM 0.2281 mL 1.1404 mL 2.2808 mL 5.7019 mL
20 mM 0.1711 mL 0.8553 mL 1.7106 mL 4.2764 mL
25 mM 0.1368 mL 0.6842 mL 1.3685 mL 3.4211 mL
30 mM 0.1140 mL 0.5702 mL 1.1404 mL 2.8510 mL
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KCNK13-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KCNK13-IN-1361368-24-3Potassium ChannelKcsAInhibitorinhibitorinhibit

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