1. GPCR/G Protein MAPK/ERK Pathway
  2. Ras
  3. KRAS G12C inhibitor 56

KRAS G12C inhibitor 56 (compound IC-6) is a potent SOS1 inhibitor with an IC50 of 1.6 nM. KRAS G12C inhibitor 56 can be used in cancer research.

For research use only. We do not sell to patients.

KRAS G12C inhibitor 56 Chemical Structure

KRAS G12C inhibitor 56 Chemical Structure

CAS No. : 2749963-77-5

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Description

KRAS G12C inhibitor 56 (compound IC-6) is a potent SOS1 inhibitor with an IC50 of 1.6 nM. KRAS G12C inhibitor 56 can be used in cancer research[1].

IC50 & Target

IC50: 1.6 nM (SOS1)[1].

Molecular Weight

617.76

Formula

C32H39N7O4S

CAS No.
SMILES

C=CC(N1CCC(CC1)OC2=NC(C3=CC([C@@]4(C)CCCC5=C4C(C#N)=C(S5)N)=NO3)=NC(O[C@H]([C@@H]6CCCN6C)C)=C2)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
KRAS G12C inhibitor 56
Cat. No.:
HY-148261
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