1. GPCR/G Protein Neuronal Signaling
  2. Somatostatin Receptor
  3. L-796778 acetate

L-796778 is a selective agonist of the sst3 receptor. In CHO-K1 cells expressing the hsst3 receptor, L-796778 is a partial agonist that inhibits Forskolin (HY-15371)-stimulated cAMP production with an IC50 value of 18 nM. L-796778 has anticonvulsant effect.

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L-796778 acetate Chemical Structure

L-796778 acetate Chemical Structure

CAS No. : 2922280-21-3

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Description

L-796778 is a selective agonist of the sst3 receptor. In CHO-K1 cells expressing the hsst3 receptor, L-796778 is a partial agonist that inhibits Forskolin (HY-15371)-stimulated cAMP production with an IC50 value of 18 nM. L-796778 has anticonvulsant effect[1].

Molecular Weight

644.72

Formula

C31H44N6O9

CAS No.
Appearance

Solid

SMILES

O=C([C@H](CCCCN)NC([C@@H](CCCC)NC(N[C@H](C(NC1=CC=C(C=C1)[N+]([O-])=O)=O)CC2=CC=CC=C2)=O)=O)OC.CC(O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
L-796778 acetate
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HY-123335A
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