L-Aspartic acid-¹³C₄,¹⁵N

Name: L-Aspartic acid- 13 C 4 , 15 N
Brand: MedChemExpress
SKU: HY-N0666S1
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0666S1 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-Aspartic acid-¹³C₄,¹⁵N is the ¹³C-labeled and ¹⁵N-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.

For research use only. We do not sell to patients.

L-Aspartic acid-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N Chemical Structure

L-Aspartic acid-¹³C₄,¹⁵N Chemical Structure

CAS No. : 202468-27-7

Size	Price	Stock	Quantity
1 mg	USD 70	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 185	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 300	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of L-Aspartic acid-¹³C₄,¹⁵N:

L-Aspartic acid In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

L-Aspartic acid-¹³C₄,¹⁵N is the ¹³C-labeled and ¹⁵N-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

138.07

Formula

¹³C₄H₇ ¹⁵NO₄

CAS No.

202468-27-7

Unlabeled CAS

56-84-8

Appearance

Solid

Color

White to off-white

SMILES

O[13C]([13CH2][13C@H]([15NH2])[13C](O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

1M NaOH : 100 mg/mL (724.27 mM; ultrasonic and adjust pH to 12 with NaOH)

1 M NaOH : 100 mg/mL (724.27 mM; ultrasonic and adjust pH to 12 with NaOH)

H₂O : 2 mg/mL (14.49 mM; ultrasonic and warming and heat to 60°C)

DMSO : 1 mg/mL (7.24 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.2427 mL	36.2135 mL	72.4270 mL
5 mM	1.4485 mL	7.2427 mL	14.4854 mL
10 mM	0.7243 mL	3.6214 mL	7.2427 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (246 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73(3):1206-11. [Content Brief]

[3]. Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug;23(4):397-406. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / DMSO / H₂O / H₂O / 1M NaOH / 1 M NaOH	1 mM	7.2427 mL	36.2135 mL	72.4270 mL	181.0676 mL
DMSO / DMSO / H₂O / H₂O / 1M NaOH / 1 M NaOH	5 mM	1.4485 mL	7.2427 mL	14.4854 mL	36.2135 mL
H₂O / H₂O / 1M NaOH / 1 M NaOH	10 mM	0.7243 mL	3.6214 mL	7.2427 mL	18.1068 mL
1M NaOH / 1 M NaOH	15 mM	0.4828 mL	2.4142 mL	4.8285 mL	12.0712 mL
	20 mM	0.3621 mL	1.8107 mL	3.6214 mL	9.0534 mL
	25 mM	0.2897 mL	1.4485 mL	2.8971 mL	7.2427 mL
	30 mM	0.2414 mL	1.2071 mL	2.4142 mL	6.0356 mL
	40 mM	0.1811 mL	0.9053 mL	1.8107 mL	4.5267 mL
	50 mM	0.1449 mL	0.7243 mL	1.4485 mL	3.6214 mL
	60 mM	0.1207 mL	0.6036 mL	1.2071 mL	3.0178 mL
	80 mM	0.0905 mL	0.4527 mL	0.9053 mL	2.2633 mL
	100 mM	0.0724 mL	0.3621 mL	0.7243 mL	1.8107 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.