1. Others Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds Endogenous Metabolite
  3. L-Cysteine-d2

L-Cysteine-d2 is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

For research use only. We do not sell to patients.

L-Cysteine-d<sub>2</sub> Chemical Structure

L-Cysteine-d2 Chemical Structure

CAS No. : 130633-02-2

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5 mg USD 206 In-stock
10 mg USD 320 In-stock
25 mg USD 650 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of L-Cysteine-d2:

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Description

L-Cysteine-d2 is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

123.17

Formula

C3H5D2NO2S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)C([2H])([2H])S)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 16.67 mg/mL (135.34 mM; ultrasonic and adjust pH to 2 with 1M HCl)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.1189 mL 40.5943 mL 81.1886 mL
5 mM 1.6238 mL 8.1189 mL 16.2377 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 8.1189 mL 40.5943 mL 81.1886 mL 202.9715 mL
5 mM 1.6238 mL 8.1189 mL 16.2377 mL 40.5943 mL
10 mM 0.8119 mL 4.0594 mL 8.1189 mL 20.2972 mL
15 mM 0.5413 mL 2.7063 mL 5.4126 mL 13.5314 mL
20 mM 0.4059 mL 2.0297 mL 4.0594 mL 10.1486 mL
25 mM 0.3248 mL 1.6238 mL 3.2475 mL 8.1189 mL
30 mM 0.2706 mL 1.3531 mL 2.7063 mL 6.7657 mL
40 mM 0.2030 mL 1.0149 mL 2.0297 mL 5.0743 mL
50 mM 0.1624 mL 0.8119 mL 1.6238 mL 4.0594 mL
60 mM 0.1353 mL 0.6766 mL 1.3531 mL 3.3829 mL
80 mM 0.1015 mL 0.5074 mL 1.0149 mL 2.5371 mL
100 mM 0.0812 mL 0.4059 mL 0.8119 mL 2.0297 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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L-Cysteine-d2
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HY-Y0337S6
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