2. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  3. Dopamine Receptor Endogenous Metabolite
  4. L-DOPA-13C

L-DOPA-13C is the 13C labeled L-DOPA[1]. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease[2][3][4].

For research use only. We do not sell to patients.

L-DOPA-<sup>13</sup>C Chemical Structure

L-DOPA-13C Chemical Structure

CAS No. : 586971-29-1

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Based on 1 publication(s) in Google Scholar

Other Forms of L-DOPA-13C:

L-DOPA-13C Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE L-DOPA-13C

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Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

  • Biological Activity

  • Purity & Documentation

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  • Customer Review

Description

L-DOPA-13C is the 13C labeled L-DOPA[1]. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease[2][3][4].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-DOPA-13C Related Antibodies
Molecular Weight

198.18

Formula

C813CH11NO4
CAS No.
Unlabeled CAS

59-92-7
Appearance

Solid

Color

White to off-white

SMILES

O[13C]([C@@H](N)CC1=CC(O)=C(C=C1)O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

0.1 M HCL : 20 mg/mL (100.92 mM; ultrasonic and warming and adjust pH to pH to 2 with HCl)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.0459 mL 25.2296 mL 50.4592 mL
5 mM 1.0092 mL 5.0459 mL 10.0918 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
0.1 M HCL 1 mM 5.0459 mL 25.2296 mL 50.4592 mL 126.1480 mL
5 mM 1.0092 mL 5.0459 mL 10.0918 mL 25.2296 mL
10 mM 0.5046 mL 2.5230 mL 5.0459 mL 12.6148 mL
15 mM 0.3364 mL 1.6820 mL 3.3639 mL 8.4099 mL
20 mM 0.2523 mL 1.2615 mL 2.5230 mL 6.3074 mL
25 mM 0.2018 mL 1.0092 mL 2.0184 mL 5.0459 mL
30 mM 0.1682 mL 0.8410 mL 1.6820 mL 4.2049 mL
40 mM 0.1261 mL 0.6307 mL 1.2615 mL 3.1537 mL
50 mM 0.1009 mL 0.5046 mL 1.0092 mL 2.5230 mL
60 mM 0.0841 mL 0.4205 mL 0.8410 mL 2.1025 mL
80 mM 0.0631 mL 0.3154 mL 0.6307 mL 1.5768 mL
100 mM 0.0505 mL 0.2523 mL 0.5046 mL 1.2615 mL
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L-DOPA-13C Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-DOPA-13C586971-29-1Dopamine ReceptorEndogenous MetaboliteInhibitorinhibitorinhibit

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