2. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  3. Dopamine Receptor Endogenous Metabolite
  4. L-DOPA-d6

L-DOPA-d6  (Synonyms: Levodopa-d6; 3,4-Dihydroxyphenylalanine-d6)

Cat. No.: HY-N0304S Purity: ≥99.0%
COA Handling Instructions

Molarity Calculator

L-DOPA-d6 is the deuterium labeled L-DOPA. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease[1][2][3].

For research use only. We do not sell to patients.

L-DOPA-d<sub>6</sub> Chemical Structure

L-DOPA-d6 Chemical Structure

CAS No. : 713140-75-1

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1 mg USD 690 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of L-DOPA-d6:

L-DOPA-d6 Related Antibodies

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Description

L-DOPA-d6 is the deuterium labeled L-DOPA. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-DOPA-d6 Related Antibodies
Molecular Weight

203.22

Formula

C9H5D6NO4
CAS No.
Unlabeled CAS

59-92-7
Appearance

Solid

Color

White to off-white

SMILES

OC([C@](N)([2H])C([2H])([2H])C1=C([2H])C(O)=C(C([2H])=C1[2H])O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

0.1 M HCL : 20 mg/mL (98.42 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)

0.1 M HCL : 20 mg/mL (98.42 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)

H2O : 1 mg/mL (4.92 mM; Need ultrasonic)

H2O : 1 mg/mL (4.92 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9208 mL 24.6039 mL 49.2078 mL
5 mM 0.9842 mL 4.9208 mL 9.8416 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

COA (253 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O / 0.1 M HCL / 0.1 M HCL 1 mM 4.9208 mL 24.6039 mL 49.2078 mL 123.0194 mL
0.1 M HCL / 0.1 M HCL 5 mM 0.9842 mL 4.9208 mL 9.8416 mL 24.6039 mL
10 mM 0.4921 mL 2.4604 mL 4.9208 mL 12.3019 mL
15 mM 0.3281 mL 1.6403 mL 3.2805 mL 8.2013 mL
20 mM 0.2460 mL 1.2302 mL 2.4604 mL 6.1510 mL
25 mM 0.1968 mL 0.9842 mL 1.9683 mL 4.9208 mL
30 mM 0.1640 mL 0.8201 mL 1.6403 mL 4.1006 mL
40 mM 0.1230 mL 0.6151 mL 1.2302 mL 3.0755 mL
50 mM 0.0984 mL 0.4921 mL 0.9842 mL 2.4604 mL
60 mM 0.0820 mL 0.4101 mL 0.8201 mL 2.0503 mL
80 mM 0.0615 mL 0.3075 mL 0.6151 mL 1.5377 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-DOPA-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-DOPA-d6713140-75-1Levodopa-d63,4-Dihydroxyphenylalanine-d6Dopamine ReceptorEndogenous MetaboliteInhibitorinhibitorinhibit

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