L-Glutamine-¹³C₅ (Synonyms: L-Glutamic acid 5-amide-¹³C₅)

Name: L-Glutamine- 13 C 5
Brand: MedChemExpress
SKU: HY-N0390S1
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0390S1 Purity: 99.93%: FAQs
Data Sheet SDS COA Handling Instructions

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L-Glutamine-¹³C₅ is the ¹³C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].

For research use only. We do not sell to patients.

L-Glutamine-<sup>13</sup>C<sub>5</sub> Chemical Structure

L-Glutamine-¹³C₅ Chemical Structure

CAS No. : 184161-19-1

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	USD 187	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 187	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 170	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 270	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 540	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 870	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of L-Glutamine-¹³C₅:

L-Glutamine In-stock

1 Publications Citing Use of MCE L-Glutamine-¹³C₅

•Nat Struct Mol Biol. 2024 May 20. [Abstract]

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mGluR1 mGluR2 mGluR3 mGluR4 mGluR5 mGluR6 mGluR7 mGluR8 mGluR

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Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

151.11

Formula

¹³C₅H₁₀N₂O₃

CAS No.

184161-19-1

Unlabeled CAS

56-85-9

Appearance

Solid

Color

White to off-white

SMILES

N[13C]([13CH2][13CH2][13C@H](N)[13C](O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 31.25 mg/mL (206.80 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.6177 mL	33.0885 mL	66.1770 mL
5 mM	1.3235 mL	6.6177 mL	13.2354 mL
10 mM	0.6618 mL	3.3088 mL	6.6177 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 16.67 mg/mL (110.32 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.93%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (248 KB) HNMR (280 KB) RP-HPLC (199 KB) MS (80 KB) OR (250 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Mary Corless , et al. Glutamine Regulates Expression of Key Transcription Factor, Signal Transduction, Metabolic Gene, and Protein Expression in a Clonal Pancreatic Beta-Cell Line. J Endocrinol. 2006 Sep;190(3):719-27. [Content Brief]

[3]. Newsholme P, et al. Glutamine and glutamate as vital metabolites. Braz J Med Biol Res. 2003 Feb;36(2):153-63. Epub 2003 Jan 29. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / H₂O	1 mM	6.6177 mL	33.0885 mL	66.1770 mL	165.4424 mL
	5 mM	1.3235 mL	6.6177 mL	13.2354 mL	33.0885 mL
	10 mM	0.6618 mL	3.3088 mL	6.6177 mL	16.5442 mL
	15 mM	0.4412 mL	2.2059 mL	4.4118 mL	11.0295 mL
	20 mM	0.3309 mL	1.6544 mL	3.3088 mL	8.2721 mL
	25 mM	0.2647 mL	1.3235 mL	2.6471 mL	6.6177 mL
	30 mM	0.2206 mL	1.1029 mL	2.2059 mL	5.5147 mL
	40 mM	0.1654 mL	0.8272 mL	1.6544 mL	4.1361 mL
	50 mM	0.1324 mL	0.6618 mL	1.3235 mL	3.3088 mL
	60 mM	0.1103 mL	0.5515 mL	1.1029 mL	2.7574 mL
	80 mM	0.0827 mL	0.4136 mL	0.8272 mL	2.0680 mL
	100 mM	0.0662 mL	0.3309 mL	0.6618 mL	1.6544 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

L-Glutamine-¹³C₅ Related Classifications

Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Glutamine-¹³C₅184161-19-1L-Glutamic acid 5-amide-¹³C₅mGluREndogenous MetaboliteFerroptosisMetabotropic glutamate receptorsInhibitorinhibitorinhibit

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L-Glutamine-13C5 (Synonyms: L-Glutamic acid 5-amide-13C5)

Customer Review

Other Forms of L-Glutamine-13C5:

L-Glutamine-13C5 Related Antibodies

1 Publications Citing Use of MCE L-Glutamine-13C5

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•Related Small Molecules:

•Related Proteins:

View All mGluR Isoform Specific Products:

Biological Activity

Purity & Documentation

References

Customer Review

L-Glutamine-13C5 Related Antibodies

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

L-Glutamine-13C5 Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

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SAFETY DATA SHEET (SDS)

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L-Glutamine-¹³C₅ (Synonyms: L-Glutamic acid 5-amide-¹³C₅)

Other Forms of L-Glutamine-¹³C₅:

L-Glutamine-¹³C₅ Related Antibodies

1 Publications Citing Use of MCE L-Glutamine-¹³C₅

L-Glutamine-¹³C₅ Related Antibodies

L-Glutamine-¹³C₅ Related Classifications