2. Others Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Endogenous Metabolite
  4. L-Histidine-15N hydrochloride hydrate

L-Histidine-15N hydrochloride hydrate  (Synonyms: H-His-OH-15N hydrochloride hydrate)

Cat. No.: HY-W014423S6 Purity: 99.24%
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L-Histidine-15N (hydrochloride hydrate) is the 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.

For research use only. We do not sell to patients.

L-Histidine-<sup>15</sup>N hydrochloride hydrate Chemical Structure

L-Histidine-15N hydrochloride hydrate Chemical Structure

Size Price Stock Quantity
1 mg USD 200 In-stock
5 mg USD 400 In-stock
10 mg USD 580 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Histidine-15N hydrochloride hydrate:

L-Histidine-15N hydrochloride hydrate Related Antibodies

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Description

L-Histidine-15N (hydrochloride hydrate) is the 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Histidine-15N hydrochloride hydrate Related Antibodies
Molecular Weight

210.62

Formula

C6H12ClN215NO3
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@]([15NH2])([H])CC1=CN=CN1.Cl.O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (593.49 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7479 mL 23.7394 mL 47.4789 mL
5 mM 0.9496 mL 4.7479 mL 9.4958 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.7479 mL 23.7394 mL 47.4789 mL 118.6972 mL
5 mM 0.9496 mL 4.7479 mL 9.4958 mL 23.7394 mL
10 mM 0.4748 mL 2.3739 mL 4.7479 mL 11.8697 mL
15 mM 0.3165 mL 1.5826 mL 3.1653 mL 7.9131 mL
20 mM 0.2374 mL 1.1870 mL 2.3739 mL 5.9349 mL
25 mM 0.1899 mL 0.9496 mL 1.8992 mL 4.7479 mL
30 mM 0.1583 mL 0.7913 mL 1.5826 mL 3.9566 mL
40 mM 0.1187 mL 0.5935 mL 1.1870 mL 2.9674 mL
50 mM 0.0950 mL 0.4748 mL 0.9496 mL 2.3739 mL
60 mM 0.0791 mL 0.3957 mL 0.7913 mL 1.9783 mL
80 mM 0.0593 mL 0.2967 mL 0.5935 mL 1.4837 mL
100 mM 0.0475 mL 0.2374 mL 0.4748 mL 1.1870 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Histidine-15N hydrochloride hydrate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Histidine-15N hydrochlorideH-His-OH-15N hydrochlorideIsotope-Labeled CompoundsEndogenous MetaboliteInhibitorinhibitorinhibit

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