2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. L-Histidine hydrochloride hydrate

L-Histidine hydrochloride hydrate  (Synonyms: H-His-OH.HCl.H2O)

Cat. No.: HY-W014423 Purity: ≥98.0%
COA Handling Instructions

Molarity Calculator

L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.

For research use only. We do not sell to patients.

L-Histidine hydrochloride hydrate Chemical Structure

L-Histidine hydrochloride hydrate Chemical Structure

CAS No. : 5934-29-2

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100 mg USD 25 In-stock
500 mg USD 50 In-stock
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L-Histidine hydrochloride hydrate Related Antibodies

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Description

L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.

Molecular Weight

209.63

Formula

C6H12ClN3O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@](N)([H])CC1=CN=CN1.Cl.O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature, keep dry and cool
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (477.03 mM; Need ultrasonic)

DMSO : 1 mg/mL (4.77 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7703 mL 23.8515 mL 47.7031 mL
5 mM 0.9541 mL 4.7703 mL 9.5406 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (238.52 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (252 KB) HNMR (260 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 4.7703 mL 23.8515 mL 47.7031 mL 119.2577 mL
H2O 5 mM 0.9541 mL 4.7703 mL 9.5406 mL 23.8515 mL
10 mM 0.4770 mL 2.3852 mL 4.7703 mL 11.9258 mL
15 mM 0.3180 mL 1.5901 mL 3.1802 mL 7.9505 mL
20 mM 0.2385 mL 1.1926 mL 2.3852 mL 5.9629 mL
25 mM 0.1908 mL 0.9541 mL 1.9081 mL 4.7703 mL
30 mM 0.1590 mL 0.7951 mL 1.5901 mL 3.9753 mL
40 mM 0.1193 mL 0.5963 mL 1.1926 mL 2.9814 mL
50 mM 0.0954 mL 0.4770 mL 0.9541 mL 2.3852 mL
60 mM 0.0795 mL 0.3975 mL 0.7951 mL 1.9876 mL
80 mM 0.0596 mL 0.2981 mL 0.5963 mL 1.4907 mL
100 mM 0.0477 mL 0.2385 mL 0.4770 mL 1.1926 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Histidine hydrochloride hydrate Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Histidine hydrochloride5934-29-2H-His-OH.HCl.H2OEndogenous MetaboliteInhibitorinhibitorinhibit

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