2. Others Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Calcium Channel iGluR Endogenous Metabolite
  4. L-Phenylalanine-13C6

L-Phenylalanine-13C6  (Synonyms: (S)-2-Amino-3-phenylpropionic acid-13C6)

Cat. No.: HY-N0215S8 Purity: 98.00%
COA Handling Instructions

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L-Phenylalanine-13C6 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

For research use only. We do not sell to patients.

L-Phenylalanine-<sup>13</sup>C<sub>6</sub> Chemical Structure

L-Phenylalanine-13C6 Chemical Structure

CAS No. : 180268-82-0

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Phenylalanine-13C6:

L-Phenylalanine-13C6 Related Antibodies

Top Publications Citing Use of Products

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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AMPA Receptor NMDA Receptor Kainate Receptor

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Description

L-Phenylalanine-13C6 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

IC50 & Target

NMDA Receptor

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Phenylalanine-13C6 Related Antibodies
Molecular Weight

171.15

Formula

C313C6H11NO2
CAS No.
Unlabeled CAS

63-91-2
Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)C[13C]1=[13CH][13CH]=[13CH][13CH]=[13CH]1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 6.67 mg/mL (38.97 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8428 mL 29.2141 mL 58.4283 mL
5 mM 1.1686 mL 5.8428 mL 11.6857 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

COA (247 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.8428 mL 29.2141 mL 58.4283 mL 146.0707 mL
5 mM 1.1686 mL 5.8428 mL 11.6857 mL 29.2141 mL
10 mM 0.5843 mL 2.9214 mL 5.8428 mL 14.6071 mL
15 mM 0.3895 mL 1.9476 mL 3.8952 mL 9.7380 mL
20 mM 0.2921 mL 1.4607 mL 2.9214 mL 7.3035 mL
25 mM 0.2337 mL 1.1686 mL 2.3371 mL 5.8428 mL
30 mM 0.1948 mL 0.9738 mL 1.9476 mL 4.8690 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Phenylalanine-13C6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Phenylalanine-13C6180268-82-0(S)-2-Amino-3-phenylpropionic acid-13C6Isotope-Labeled CompoundsCalcium ChanneliGluREndogenous MetaboliteCa2+ channelsCa channelsIonotropic glutamate receptorsInhibitorinhibitorinhibit

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