2. Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease
  3. Calcium Channel iGluR Endogenous Metabolite
  4. L-Phenylalanine-13C9,15N

L-Phenylalanine-13C9,15N  (Synonyms: (S)-2-Amino-3-phenylpropionic acid-13C9,15N)

Cat. No.: HY-N0215S11 Purity: 99.52%
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L-Phenylalanine-13C9,15N is the 13C- and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

For research use only. We do not sell to patients.

L-Phenylalanine-<sup>13</sup>C<sub>9</sub>,<sup>15</sup>N Chemical Structure

L-Phenylalanine-13C9,15N Chemical Structure

CAS No. : 878339-23-2

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10 mg USD 330 In-stock
25 mg USD 650 In-stock
50 mg USD 1000 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of L-Phenylalanine-13C9,15N:

L-Phenylalanine-13C9,15N Related Antibodies

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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AMPA Receptor NMDA Receptor Kainate Receptor

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Description

L-Phenylalanine-13C9,15N is the 13C- and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

IC50 & Target

NMDA Receptor

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Phenylalanine-13C9,15N Related Antibodies
Molecular Weight

175.12

Formula

13C9H1115NO2
CAS No.
Unlabeled CAS

63-91-2
Appearance

Solid

Color

White to off-white

SMILES

O[13C]([13C@@H]([13CH2][13C]1=[13CH][13CH]=[13CH][13CH]=[13CH]1)[15NH2])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 20.83 mg/mL (118.95 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.7104 mL 28.5519 mL 57.1037 mL
5 mM 1.1421 mL 5.7104 mL 11.4207 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.7104 mL 28.5519 mL 57.1037 mL 142.7593 mL
5 mM 1.1421 mL 5.7104 mL 11.4207 mL 28.5519 mL
10 mM 0.5710 mL 2.8552 mL 5.7104 mL 14.2759 mL
15 mM 0.3807 mL 1.9035 mL 3.8069 mL 9.5173 mL
20 mM 0.2855 mL 1.4276 mL 2.8552 mL 7.1380 mL
25 mM 0.2284 mL 1.1421 mL 2.2841 mL 5.7104 mL
30 mM 0.1903 mL 0.9517 mL 1.9035 mL 4.7586 mL
40 mM 0.1428 mL 0.7138 mL 1.4276 mL 3.5690 mL
50 mM 0.1142 mL 0.5710 mL 1.1421 mL 2.8552 mL
60 mM 0.0952 mL 0.4759 mL 0.9517 mL 2.3793 mL
80 mM 0.0714 mL 0.3569 mL 0.7138 mL 1.7845 mL
100 mM 0.0571 mL 0.2855 mL 0.5710 mL 1.4276 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Phenylalanine-13C9,15N Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Phenylalanine-13C9,15N878339-23-2(S)-2-Amino-3-phenylpropionic acid-13C9,15NCalcium ChanneliGluREndogenous MetaboliteCa2+ channelsCa channelsIonotropic glutamate receptorsInhibitorinhibitorinhibit

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