2. Others Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Calcium Channel iGluR Endogenous Metabolite
  4. L-Phenylalanine-13C9

L-Phenylalanine-13C9  (Synonyms: (S)-2-Amino-3-phenylpropionic acid-13C9)

Cat. No.: HY-N0215S10 Purity: 98%
COA Handling Instructions

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L-Phenylalanine-13C9 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

For research use only. We do not sell to patients.

L-Phenylalanine-<sup>13</sup>C<sub>9</sub> Chemical Structure

L-Phenylalanine-13C9 Chemical Structure

CAS No. : 439685-11-7

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Phenylalanine-13C9:

L-Phenylalanine-13C9 Related Antibodies

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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AMPA Receptor NMDA Receptor Kainate Receptor

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Description

L-Phenylalanine-13C9 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

IC50 & Target

NMDA Receptor

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Phenylalanine-13C9 Related Antibodies
Molecular Weight

174.12

Formula

13C9H11NO2
CAS No.
Unlabeled CAS

63-91-2
Appearance

Solid

Color

White to off-white

SMILES

O[13C]([13C@@H](N)[13CH2][13C]1=[13CH][13CH]=[13CH][13CH]=[13CH]1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 98%

COA (247 KB)

Handling Instructions (2659 KB)
References
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L-Phenylalanine-13C9 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Phenylalanine-13C9439685-11-7(S)-2-Amino-3-phenylpropionic acid-13C9Isotope-Labeled CompoundsCalcium ChanneliGluREndogenous MetaboliteCa2+ channelsCa channelsIonotropic glutamate receptorsInhibitorinhibitorinhibit

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