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  2. Amino Acid Derivatives
  3. L-Prolyl-L-leucine

L-Prolyl-L-leucine is a leucine derivative.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

L-Prolyl-L-leucine Chemical Structure

L-Prolyl-L-leucine Chemical Structure

CAS No. : 52899-07-7

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Based on 1 publication(s) in Google Scholar

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Description

L-Prolyl-L-leucine is a leucine derivative[1].

In Vitro

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

228.29

Formula

C11H20N2O3

CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 40 mg/mL (175.22 mM; adjust pH to 1 with TFA)

DMSO : 4.2 mg/mL (18.40 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3804 mL 21.9020 mL 43.8039 mL
5 mM 0.8761 mL 4.3804 mL 8.7608 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 4.3804 mL 21.9020 mL 43.8039 mL 109.5098 mL
5 mM 0.8761 mL 4.3804 mL 8.7608 mL 21.9020 mL
10 mM 0.4380 mL 2.1902 mL 4.3804 mL 10.9510 mL
15 mM 0.2920 mL 1.4601 mL 2.9203 mL 7.3007 mL
H2O 20 mM 0.2190 mL 1.0951 mL 2.1902 mL 5.4755 mL
25 mM 0.1752 mL 0.8761 mL 1.7522 mL 4.3804 mL
30 mM 0.1460 mL 0.7301 mL 1.4601 mL 3.6503 mL
40 mM 0.1095 mL 0.5475 mL 1.0951 mL 2.7377 mL
50 mM 0.0876 mL 0.4380 mL 0.8761 mL 2.1902 mL
60 mM 0.0730 mL 0.3650 mL 0.7301 mL 1.8252 mL
80 mM 0.0548 mL 0.2738 mL 0.5475 mL 1.3689 mL
100 mM 0.0438 mL 0.2190 mL 0.4380 mL 1.0951 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
L-Prolyl-L-leucine
Cat. No.:
HY-W009686
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