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  3. Amino Acid Derivatives
  4. L-γ-Glutamyl-p-nitroanilide

L-γ-Glutamyl-p-nitroanilide 

Cat. No.: HY-W011391A Purity: ≥97.0%
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L-γ-Glutamyl-p-nitroanilide Monohydrate is a glutamic acid derivative.

For research use only. We do not sell to patients.

L-γ-Glutamyl-p-nitroanilide Chemical Structure

L-γ-Glutamyl-p-nitroanilide Chemical Structure

CAS No. : 7300-59-6

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Other Forms of L-γ-Glutamyl-p-nitroanilide:

L-γ-Glutamyl-p-nitroanilide Related Antibodies

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Description

L-γ-Glutamyl-p-nitroanilide Monohydrate is a glutamic acid derivative[1].

Cellular Effect
Cell Line Type Value Description References
C6 IC50
70.2 μM
Compound: 1; GPNA
Inhibition of ASCT2-mediated glutamine transport in rat C6 cells using [3H]-glutamine after 15 mins by scintillation counting
Inhibition of ASCT2-mediated glutamine transport in rat C6 cells using [3H]-glutamine after 15 mins by scintillation counting
[PMID: 26750251]
HEK293 IC50
1.2 mM
Compound: 1; GPNA
Inhibition of ASCT2-mediated glutamine transport in human HEK293 cells using [3H]-glutamine after 15 mins by scintillation counting
Inhibition of ASCT2-mediated glutamine transport in human HEK293 cells using [3H]-glutamine after 15 mins by scintillation counting
[PMID: 26750251]
HEK293 IC50
954 μM
Compound: 1
Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assay
Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assay
[PMID: 25435145]
In Vitro

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-γ-Glutamyl-p-nitroanilide Related Antibodies
Molecular Weight

267.24

Formula

C11H13N3O5
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

OC([C@@H](N)CCC(NC1=CC=C([N+]([O-])=O)C=C1)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (46.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7420 mL 18.7098 mL 37.4195 mL
5 mM 0.7484 mL 3.7420 mL 7.4839 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7420 mL 18.7098 mL 37.4195 mL 93.5489 mL
5 mM 0.7484 mL 3.7420 mL 7.4839 mL 18.7098 mL
10 mM 0.3742 mL 1.8710 mL 3.7420 mL 9.3549 mL
15 mM 0.2495 mL 1.2473 mL 2.4946 mL 6.2366 mL
20 mM 0.1871 mL 0.9355 mL 1.8710 mL 4.6774 mL
25 mM 0.1497 mL 0.7484 mL 1.4968 mL 3.7420 mL
30 mM 0.1247 mL 0.6237 mL 1.2473 mL 3.1183 mL
40 mM 0.0935 mL 0.4677 mL 0.9355 mL 2.3387 mL
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L-γ-Glutamyl-p-nitroanilide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-γ-Glutamyl-p-nitroanilide7300-59-6Amino Acid DerivativesInhibitorinhibitorinhibit

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