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  4. Lactate (sodium) (60% in water)

Lactate (sodium) (60% in water)  (Synonyms: Lactic acid sodium)

Cat. No.: HY-B2227B Purity: ≥98.0%
SDS
COA
Handling Instructions Technical Support

Lactate (60% in water) (Lactic acid) sodium is the product of glycogenolysis and glycolysis. Lactate sodium (60% in water) is an organic salt that is mainly used as a buffer and pH adjuster for injection solutions. Lactate sodium (60% in water) can be metabolized by the body into sodium bicarbonate, which in turn acts to increase the pH of the blood. Lactate sodium (60% in water) is used to improve metabolic acidosis and hypovolemic states. In terms of pharmaceutical preparations, Lactate sodium (60% in water) is often used in combination with sodium chloride, glucose, etc. to form normal saline or compound liquid intravenous injection. Lactate sodium (60% in water) also has antimicrobial activity, which can be used as a food preservative.

For research use only. We do not sell to patients.

Lactate (sodium) (60% in water) Chemical Structure

Lactate (sodium) (60% in water) Chemical Structure

CAS No. : 72-17-3

Size Price Stock Quantity
Solvent
100 mg (5.34 M * 167 μL in Water) In-stock
Solvent
250 mg (5.34 M * 418 μL in Water) In-stock
Solvent
500 mg (5.34 M * 835 μL in Water) In-stock
Solvent
1 g (5.34 M * 1.67 mL in Water) In-stock

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Customer Review

Based on 24 publication(s) in Google Scholar

Other Forms of Lactate (sodium) (60% in water):

Lactate (sodium) (60% in water) Related Antibodies

Top Publications Citing Use of Products

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: Redox Biol. 2025 Feb 15:81:103553.  [Abstract]

    Immunoblot and quantification analyses of NFS1 in HCC cells incubated with 0, 5, or 10 mM lactate after being subjected to either a 47 °C or 37 °C water bath.

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Feb 28;16(1):144.  [Abstract]

    Lactate (25 mM) significantly increases the mRNA and protein expression of FBXO33.

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Feb 28;16(1):144.  [Abstract]

    Co-IP detected the effect of lactate on YY1 protein lactylation modification.

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Mar 20;16(1):193.  [Abstract]

    Lactate sodium (5-15 mM; 24 h) ​​results​​ in increased H4K12la (red) levels in CCSCs compared to the control group.

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2024 Mar 5;43(1):68.  [Abstract]

    Lactate sodium increases IGF-1R levels in PI-resistant KAS-6/1 and U266 cells.

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: Cell Res. 2023 Sep;33(9):679-698.  [Abstract]

    Lactate (NALA) (300 mM; 24 h) significantly upregulates α-MHC K1897 lactylation in H9c2 cells.

    Lactate (sodium) (60% in water) purchased from MedChemExpress. Usage Cited in: J Ginseng Res. 2023 Dec 27.

    The expression level of METTL3, YTHDF1, YTHDF2, and YTHDC1 in NB4-R1 and NB4-R2 cells treated with 20 μM oxamate or 20 μM lactate or 1 μM ATRA for 48 h was detected via qRT-PCR.

    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    Lactate (60% in water) (Lactic acid) sodium is the product of glycogenolysis and glycolysis[1]. Lactate sodium (60% in water) is an organic salt that is mainly used as a buffer and pH adjuster for injection solutions. Lactate sodium (60% in water) can be metabolized by the body into sodium bicarbonate, which in turn acts to increase the pH of the blood. Lactate sodium (60% in water) is used to improve metabolic acidosis and hypovolemic states. In terms of pharmaceutical preparations, Lactate sodium (60% in water) is often used in combination with sodium chloride, glucose, etc. to form normal saline or compound liquid intravenous injection[2][3][4][5]. Lactate sodium (60% in water) also has antimicrobial activity, which can be used as a food preservative[6].

    In Vitro

    Hypertonic Lactate sodium solution improved cognitive function in rats with traumatic brain injury (TBI). Hyperlactate sodium solution also decreased intracranial pressure (ICP) and increased cerebral blood flow by arteriole dilation[2][3].
    Lactate sodium inhibits the proliferation of various decrepit microorganisms, including aerobic and chillophilic bacteria, pseudomonas, lactic acid bacteria and Enterobacteriaceae[6].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Lactate (sodium) (60% in water) Related Antibodies
    In Vivo

    The pH of the working solution needs to be adjusted to around 7.4 before administration to animals.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
    Clinical Trial
    Molecular Weight

    112.06

    Formula

    C3H5NaO3
    CAS No.
    Appearance

    Liquid

    Color

    Colorless to light yellow

    SMILES

    [Na].O=C(O)C(O)C
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Solution, -20°C, 2 years
    Solvent & Solubility
    In Vitro: 

    H2O : 350 mg/mL (3123.33 mM; Need ultrasonic)

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

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    (per animal)

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    Dosing volume
    (per animal)

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    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: ≥98.0%

    SDS (393 KB)

    COA (249 KB)

    Handling Instructions (2659 KB)
    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 8.9238 mL 44.6190 mL 89.2379 mL 223.0948 mL
    5 mM 1.7848 mL 8.9238 mL 17.8476 mL 44.6190 mL
    10 mM 0.8924 mL 4.4619 mL 8.9238 mL 22.3095 mL
    15 mM 0.5949 mL 2.9746 mL 5.9492 mL 14.8730 mL
    20 mM 0.4462 mL 2.2309 mL 4.4619 mL 11.1547 mL
    25 mM 0.3570 mL 1.7848 mL 3.5695 mL 8.9238 mL
    30 mM 0.2975 mL 1.4873 mL 2.9746 mL 7.4365 mL
    40 mM 0.2231 mL 1.1155 mL 2.2309 mL 5.5774 mL
    50 mM 0.1785 mL 0.8924 mL 1.7848 mL 4.4619 mL
    60 mM 0.1487 mL 0.7436 mL 1.4873 mL 3.7182 mL
    80 mM 0.1115 mL 0.5577 mL 1.1155 mL 2.7887 mL
    100 mM 0.0892 mL 0.4462 mL 0.8924 mL 2.2309 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Lactate (sodium) (60% in water) Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Lactate (sodium) (60% in water)72-17-3Lactic acidBacterialglycogenolysisglycolysisInhibitorinhibitorinhibit

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