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  2. Isotope-Labeled Compounds
  3. Levomefolic acid-13C,d3

Levomefolic acid-13C,d3  (Synonyms: L-5-MTHF-13C,d3)

Cat. No.: HY-14781S1 Purity: ≥95.0%
COA Handling Instructions

Levomefolic acid-13C,d3is the deuterium labeledLevomefolic acid(HY-14781). Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements.

For research use only. We do not sell to patients.

Levomefolic acid-<sup>13</sup>C,d<sub>3</sub> Chemical Structure

Levomefolic acid-13C,d3 Chemical Structure

CAS No. : 1356019-94-7

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1 mg USD 1080 In-stock
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Description

Levomefolic acid-13C,d3is the deuterium labeledLevomefolic acid(HY-14781)[1]. Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements[2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

463.47

Formula

C1913CH22D3N7O6

CAS No.
Unlabeled CAS

31690-09-2

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(NC[C@@H]2N([13C]([2H])([2H])[2H])C3=C(N=C(N)NC3=O)NC2)C=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 2.08 mg/mL (4.49 mM; ultrasonic and warming and heat to 60°C)

H2O : 2.08 mg/mL (4.49 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1576 mL 10.7882 mL 21.5764 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 2.1576 mL 10.7882 mL 21.5764 mL 53.9409 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Levomefolic acid-13C,d3
Cat. No.:
HY-14781S1
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