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  4. Leguminosae Cancer Flavones Polyphenols
  5. Glycyrrhiza uralensis Fisch.
  6. Licoflavone C

Licoflavone C is a prenyl-flavone extracted from Genista ephedroides, reduces the genotoxicity of cancer agents in human peripheral lymphocytes.

For research use only. We do not sell to patients.

Licoflavone C Chemical Structure

Licoflavone C Chemical Structure

CAS No. : 72357-31-4

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Based on 1 publication(s) in Google Scholar

Licoflavone C Related Antibodies

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Description

Licoflavone C is a prenyl-flavone extracted from Genista ephedroides, reduces the genotoxicity of cancer agents in human peripheral lymphocytes[1].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
> 40 μM
Compound: 2
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation by MTT assay
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation by MTT assay
[PMID: 33609662]
HepG2 IC50
> 40 μM
Compound: 2
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation by MTT assay
[PMID: 33609662]
MCF7 IC50
> 40 μM
Compound: 2
Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation by MTT assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation by MTT assay
[PMID: 33609662]
NCI-H460 IC50
> 40 μM
Compound: 2
Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell proliferation by MTT assay
Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell proliferation by MTT assay
[PMID: 33609662]
RAW264.7 IC50
3.83 μM
Compound: 43
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess reagent based assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess reagent based assay
[PMID: 28522265]
Molecular Weight

338.35

Formula

C20H18O5
CAS No.
Appearance

Solid

Color

Light yellow to brown

SMILES

O=C1C=C(C2=CC=C(O)C=C2)OC3=C(C/C=C(C)\C)C(O)=CC(O)=C13
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (184.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9555 mL 14.7776 mL 29.5552 mL
5 mM 0.5911 mL 2.9555 mL 5.9110 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.89%

SDS (393 KB)

COA (249 KB) LCMS (202 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9555 mL 14.7776 mL 29.5552 mL 73.8880 mL
5 mM 0.5911 mL 2.9555 mL 5.9110 mL 14.7776 mL
10 mM 0.2956 mL 1.4778 mL 2.9555 mL 7.3888 mL
15 mM 0.1970 mL 0.9852 mL 1.9703 mL 4.9259 mL
20 mM 0.1478 mL 0.7389 mL 1.4778 mL 3.6944 mL
25 mM 0.1182 mL 0.5911 mL 1.1822 mL 2.9555 mL
30 mM 0.0985 mL 0.4926 mL 0.9852 mL 2.4629 mL
40 mM 0.0739 mL 0.3694 mL 0.7389 mL 1.8472 mL
50 mM 0.0591 mL 0.2956 mL 0.5911 mL 1.4778 mL
60 mM 0.0493 mL 0.2463 mL 0.4926 mL 1.2315 mL
80 mM 0.0369 mL 0.1847 mL 0.3694 mL 0.9236 mL
100 mM 0.0296 mL 0.1478 mL 0.2956 mL 0.7389 mL
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Licoflavone C Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Licoflavone C72357-31-4OthersInhibitorinhibitorinhibit

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