1. Apoptosis
  2. Apoptosis
  3. Lilotomab

Lilotomab  (Synonyms: HH1)

Cat. No.: HY-P99707 Purity: 98.99%
COA

Lilotomab (0-40 µg/mL; 12 days) reduces the clonogenic survival of DOHH2 and Ramos cells.
Lilotomab (40 µg/mL; 18 h) induces slight apoptosis in DOHH2 cells.

Lilotomab (HH1) is a murine anti-CD37 monoclonal antibody. Lilotomab reduces clonogenic survival. Lilotomab shows anti-tumor activity.

For research use only. We do not sell to patients.

CAS No. : 1453362-55-4

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Based on 1 publication(s) in Google Scholar

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Description

Lilotomab (HH1) is a murine anti-CD37 monoclonal antibody. Lilotomab reduces clonogenic survival. Lilotomab shows anti-tumor activity[1].

Isotype

Mouse IgG1 kappa

Recommend Isotype Controls
Species

Mouse

IC50 & Target

CD37[1]

In Vitro

Lilotomab (0-40 µg/mL; 12 days) reduces the clonogenic survival of DOHH2 and Ramos cells[1].
Lilotomab (40 µg/mL; 18 h) induces slight apoptosis in DOHH2 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis[1]

Cell Line: Ramos, DOHH2, Rec-1 cells
Concentration: 40 µg/mL
Incubation Time: 18 h
Result: Induced apoptosis in DOHH2 cells.
In Vivo

Lilotomab (0.5 mg/kg; i.v.; once) inhibits tumor growth in mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: SCID mice (DOHH2 cell xenografts)[1]
Dosage: 0.5 mg/kg
Administration: I.v.; once
Result: Inhibited tumor growth and increased mouse survival.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Lilotomab]

Shipping

Shipping with dry ice.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • IgG1-kappa
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Lilotomab
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HY-P99707
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