2. Anti-infection
  3. Bacterial Antibiotic
  4. Lincomycin hydrochloride

Lincomycin hydrochloride  (Synonyms: U10149A)

Cat. No.: HY-B0417A Purity: 99.29%
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Lincomycin Hydrochloride(U10149A) is an antibiotic produced by Streptomyces lincolnensis var.

For research use only. We do not sell to patients.

Lincomycin hydrochloride Chemical Structure

Lincomycin hydrochloride Chemical Structure

CAS No. : 859-18-7

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Based on 2 publication(s) in Google Scholar

Other Forms of Lincomycin hydrochloride:

Lincomycin hydrochloride Related Antibodies

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Description

Lincomycin Hydrochloride(U10149A) is an antibiotic produced by Streptomyces lincolnensis var. lincolnensis. Target: Antibacterial Lincomycin hydrochloride is a systemic antibiotic, which is active against most common gram positive bacteria. It has proved to be excellent for infectious diseases like acne, anthrax, pneumonia, and also for the treatment of furunculosis, carbuncles, impetigo, burns and wounds, carrying to gram positive bacteria. Lincomycin hydrochloride inhibits cell growth and microbial protein synthesis, by interacting strongly and specifically with the 50S ribosomal subunit, at mutually related sites [1-3].

Clinical Trial
Molecular Weight

443.00

Formula

C18H35ClN2O6S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@H](O)[C@@]([C@@]([C@@H]([C@H](O)[C@H]1O)O)([H])O[C@@H]1SC)([H])NC([C@@H]2C[C@@H](CCC)CN2C)=O.Cl
Structure Classification
Initial Source

Streptomyces lincolnensis
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (225.73 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2573 mL 11.2867 mL 22.5734 mL
5 mM 0.4515 mL 2.2573 mL 4.5147 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

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=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.2573 mL 11.2867 mL 22.5734 mL 56.4334 mL
5 mM 0.4515 mL 2.2573 mL 4.5147 mL 11.2867 mL
10 mM 0.2257 mL 1.1287 mL 2.2573 mL 5.6433 mL
15 mM 0.1505 mL 0.7524 mL 1.5049 mL 3.7622 mL
20 mM 0.1129 mL 0.5643 mL 1.1287 mL 2.8217 mL
25 mM 0.0903 mL 0.4515 mL 0.9029 mL 2.2573 mL
30 mM 0.0752 mL 0.3762 mL 0.7524 mL 1.8811 mL
40 mM 0.0564 mL 0.2822 mL 0.5643 mL 1.4108 mL
50 mM 0.0451 mL 0.2257 mL 0.4515 mL 1.1287 mL
60 mM 0.0376 mL 0.1881 mL 0.3762 mL 0.9406 mL
80 mM 0.0282 mL 0.1411 mL 0.2822 mL 0.7054 mL
100 mM 0.0226 mL 0.1129 mL 0.2257 mL 0.5643 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Lincomycin hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lincomycin859-18-7U10149ABacterialAntibioticInhibitorinhibitorinhibit

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