Linoleic acid-d₅

Cat. No.: HY-N0729S4 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Linoleic Acid-d₅ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism.

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Linoleic acid-d<sub>5</sub> Chemical Structure

Linoleic acid-d₅ Chemical Structure

CAS No. : 1169764-58-2

Size	Price	Stock	Quantity
Solvent
500 μg（35.03 mM * 50 μL in Ethanol）	USD 260	In-stock	Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

Other Forms of Linoleic acid-d₅:

Linoleic acid In-stock

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Biological Activity
Purity & Documentation
References
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Description	Linoleic Acid-d₅ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism^[1]^[2].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Linoleic acid-d₅ Related Antibodies
Molecular Weight	285.48
Formula	C₁₈H₂₇D₅O₂
CAS No.	1169764-58-2
Unlabeled CAS	60-33-3
Appearance	Liquid
Color	Colorless to light yellow
SMILES	O=C(O)CCCCCCC/C=C\C/C=C\CCCC([2H])([2H])C([2H])([2H])[2H]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Solution, -20°C, 2 years
Solvent & Solubility	In Vitro: DMSO : 100 mg/mL (350.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) DMSO : 100 mg/mL (350.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) 0.1 M NaOH : 8.33 mg/mL (29.18 mM; ultrasonic and warming and adjust pH to 11 with NaOH and heat to 60°C) 0.1 M NaOH : 8.33 mg/mL (29.18 mM; ultrasonic and warming and adjust pH to 11 with NaOH and heat to 60°C) Molarity Calculator Dilution Calculator Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Mass = Concentration × Volume × Molecular Weight * Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final) This equation is commonly abbreviated as: C₁V₁ = C₂V₂ Concentration _(start) C1 × Volume _(start) V1 = Concentration _(final) C2 × Volume _(final) V2 In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kg Animal weight (per animal) g Dosing volume (per animal) μL Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Calculation results: Working solution concentration: mg/mL
Purity & Documentation	Purity: ≥98.0% Select Batch: Data Sheet (263 KB) SDS (251 KB) COA (239 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief] [2]. Jay Whelan. Linoleic Acid. Adv Nutr. 2013 May; 4(3): 311–312. [Content Brief]

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

0.1 M NaOH / 0.1 M NaOH / DMSO / DMSO	1 mM	3.5029 mL	17.5144 mL	35.0287 mL	87.5718 mL
	5 mM	0.7006 mL	3.5029 mL	7.0057 mL	17.5144 mL
	10 mM	0.3503 mL	1.7514 mL	3.5029 mL	8.7572 mL
	15 mM	0.2335 mL	1.1676 mL	2.3352 mL	5.8381 mL
	20 mM	0.1751 mL	0.8757 mL	1.7514 mL	4.3786 mL
	25 mM	0.1401 mL	0.7006 mL	1.4011 mL	3.5029 mL
DMSO / DMSO	30 mM	0.1168 mL	0.5838 mL	1.1676 mL	2.9191 mL
	40 mM	0.0876 mL	0.4379 mL	0.8757 mL	2.1893 mL
	50 mM	0.0701 mL	0.3503 mL	0.7006 mL	1.7514 mL
	60 mM	0.0584 mL	0.2919 mL	0.5838 mL	1.4595 mL
	80 mM	0.0438 mL	0.2189 mL	0.4379 mL	1.0946 mL
	100 mM	0.0350 mL	0.1751 mL	0.3503 mL	0.8757 mL