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  3. Lipid A-11

Lipid A-11 (A-11) can be used to synthesize lipid-like nanoparticles (LNPs) for delivery of nucleic acids.

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Lipid A-11 Chemical Structure

Lipid A-11 Chemical Structure

CAS No. : 2996998-09-3

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Description

Lipid A-11 (A-11) can be used to synthesize lipid-like nanoparticles (LNPs) for delivery of nucleic acids[1].

Molecular Weight

1013.39

Formula

C55H100N2O14

CAS No.
Appearance

Liquid (Density: 1.038±0.06 g/cm3)

SMILES

O=C(N(CCOC(CC(COC(CCCCCCCC)=O)COC(CCCCCCCC)=O)=O)CCOC(CC(COC(CCCCCCCC)=O)COC(CCCCCCCC)=O)=O)OCCN(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (9.87 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9868 mL 4.9339 mL 9.8679 mL
5 mM 0.1974 mL 0.9868 mL 1.9736 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9868 mL 4.9339 mL 9.8679 mL 24.6697 mL
5 mM 0.1974 mL 0.9868 mL 1.9736 mL 4.9339 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Lipid A-11
Cat. No.:
HY-170333
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