2. Epigenetics PI3K/Akt/mTOR
  3. AMPK
  4. Lipid-lowering agent-2

Lipid-lowering agent-2 (Compound 14d) is an orally active lipid-lowering agent with an EC50 of 0.06 μM. Lipid-lowering agent-2 inhibits the lipid synthesis, activates the AMPK signaling pathway, and exhibits anti-obesity effect. Lipid-lowering agent-2 inhibits food intake, improves the glucose metabolism, and reduces the body weight and adipose tissue in high-fat diet (HFD)-induced obese mice.

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Lipid-lowering agent-2 Chemical Structure

Lipid-lowering agent-2 Chemical Structure

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Lipid-lowering agent-2 Related Antibodies

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Description

Lipid-lowering agent-2 (Compound 14d) is an orally active lipid-lowering agent with an EC50 of 0.06 μM. Lipid-lowering agent-2 inhibits the lipid synthesis, activates the AMPK signaling pathway, and exhibits anti-obesity effect. Lipid-lowering agent-2 inhibits food intake, improves the glucose metabolism, and reduces the body weight and adipose tissue in high-fat diet (HFD)-induced obese mice[1].

Molecular Weight

441.53

Formula

C25H27N7O
SMILES

O=C(N/N=C/C1=C(NC2=CC=CC=C21)C3=NC4=C(C(NCCN5CCCC5)=N3)C=CC=C4)C
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Lipid-lowering agent-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lipid-lowering agent-2AMPKAMP-activated protein kinaseanti-obesityorally active3T3-L1C57BL/6 mouseInhibitorinhibitorinhibit

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