2. Autophagy Protein Tyrosine Kinase/RTK JAK/STAT Signaling Epigenetics Stem Cell/Wnt PI3K/Akt/mTOR
  3. LRRK2 JAK AMPK
  4. LRRK2/NUAK1/TYK2-IN-1

LRRK2/NUAK1/TYK2-IN-1 (conpound 226) shows inhibitory activity toward LRRK2 (Wt), LRRK2 (G2019), TYK2 and NUAK1, with IC50 values lower than 10 nM. LRRK2/NUAK1/TYK2-IN-1 can be used for autoimmune disease research.

For research use only. We do not sell to patients.

LRRK2/NUAK1/TYK2-IN-1 Chemical Structure

LRRK2/NUAK1/TYK2-IN-1 Chemical Structure

CAS No. : 2629192-96-5

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LRRK2/NUAK1/TYK2-IN-1 Related Antibodies

Top Publications Citing Use of Products

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JAK1 JAK2 JAK3 Tyk2 JAK

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NUAK1 NUAK2 AMPK AMPK α1β1γ1 AMPK α2β1γ1 AMPK α1β2γ1 AMPK α2β2γ1

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Description

LRRK2/NUAK1/TYK2-IN-1 (conpound 226) shows inhibitory activity toward LRRK2 (Wt), LRRK2 (G2019), TYK2 and NUAK1, with IC50 values lower than 10 nM. LRRK2/NUAK1/TYK2-IN-1 can be used for autoimmune disease research[1].

IC50 & Target

Tyk2

 

NUAK1

 

Molecular Weight

392.34

Formula

C20H11F3N6
CAS No.
SMILES

FC1=CC=CC(F)=C1C2=NC3=C(C4=NNC=C4N2)C=C(F)C(C5=CC=NN=C5)=C3
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Room temperature in continental US; may vary elsewhere.
Storage

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Purity & Documentation
References
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LRRK2/NUAK1/TYK2-IN-1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LRRK2/NUAK1/TYK2-IN-12629192-96-5LRRK2JAKAMPKLeucine-rich repeat kinase 2Janus kinaseAMP-activated protein kinaseautoimmune diseasetyrosine-protein kinase 2Inhibitorinhibitorinhibit

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