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  4. LSN3353871

LSN3353871 is a potent inhibitor of lipoprotein(a) (Lp(a)) that can binds to Kringle IV (KIV) 8, KIV7–8 and KIV5–8, with Kd of 756 nM, 605 nM and 423 nM, respectively. LSN3353871 disrupts the formation of Lp(a) with the IC50 of 1.69 µM. LSN3353871 has oral bioactivity.

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LSN3353871 Chemical Structure

LSN3353871 Chemical Structure

CAS No. : 2565657-20-5

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LSN3353871 Related Antibodies

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Description

LSN3353871 is a potent inhibitor of lipoprotein(a) (Lp(a)) that can binds to Kringle IV (KIV) 8, KIV7–8 and KIV5–8, with Kd of 756 nM, 605 nM and 423 nM, respectively. LSN3353871 disrupts the formation of Lp(a) with the IC50 of 1.69 µM. LSN3353871 has oral bioactivity[1].

Molecular Weight

255.74

Formula

C13H18ClNO2
CAS No.
SMILES

OC([C@@H](CC1=CC=CC=C1)[C@@H]2CNCC2)=O.Cl
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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LSN3353871 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LSN33538712565657-20-5LSN 3353871LSN-3353871Otherslow-density lipoproteincynomolgus monkeysInhibitorinhibitorinhibit

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HY-158424
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