2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. LY 165163

LY 165163  (Synonyms: p-NH2-PE-TFMPP)

Cat. No.: HY-124501 Purity: 99.24%
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LY 165163 is a potent 5-HT presynaptic receptor agonist. LY 165163 significantly decreases 5-HTP accumulation and increases DOPA accumulation in the cortex and striatum.

For research use only. We do not sell to patients.

LY 165163 Chemical Structure

LY 165163 Chemical Structure

CAS No. : 1814-64-8

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5 mg USD 160 In-stock
10 mg USD 260 In-stock
25 mg USD 520 In-stock
50 mg USD 830 In-stock
100 mg USD 1330 In-stock
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Based on 1 publication(s) in Google Scholar

LY 165163 Related Antibodies

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Description

LY 165163 is a potent 5-HT presynaptic receptor agonist. LY 165163 significantly decreases 5-HTP accumulation and increases DOPA accumulation in the cortex and striatum[1].

Molecular Weight

349.39

Formula

C19H22F3N3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC1=CC=C(C=C1)CCN2CCN(CC2)C3=CC=CC(C(F)(F)F)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 50 mg/mL (143.11 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8621 mL 14.3107 mL 28.6213 mL
5 mM 0.5724 mL 2.8621 mL 5.7243 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 2.8621 mL 14.3107 mL 28.6213 mL 71.5533 mL
5 mM 0.5724 mL 2.8621 mL 5.7243 mL 14.3107 mL
10 mM 0.2862 mL 1.4311 mL 2.8621 mL 7.1553 mL
15 mM 0.1908 mL 0.9540 mL 1.9081 mL 4.7702 mL
20 mM 0.1431 mL 0.7155 mL 1.4311 mL 3.5777 mL
25 mM 0.1145 mL 0.5724 mL 1.1449 mL 2.8621 mL
30 mM 0.0954 mL 0.4770 mL 0.9540 mL 2.3851 mL
40 mM 0.0716 mL 0.3578 mL 0.7155 mL 1.7888 mL
50 mM 0.0572 mL 0.2862 mL 0.5724 mL 1.4311 mL
60 mM 0.0477 mL 0.2385 mL 0.4770 mL 1.1926 mL
80 mM 0.0358 mL 0.1789 mL 0.3578 mL 0.8944 mL
100 mM 0.0286 mL 0.1431 mL 0.2862 mL 0.7155 mL
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LY 165163 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LY 1651631814-64-8p-NH2-PE-TFMPPLY165163LY-1651635-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorpresynapticInhibitorinhibitorinhibit

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