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LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor.

For research use only. We do not sell to patients.

LY-402913 Chemical Structure

LY-402913 Chemical Structure

CAS No. : 334970-65-9

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1 mg USD 190 In-stock
5 mg USD 450 In-stock
10 mg USD 650 Get quote
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Description

LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor[1].

Molecular Weight

533.96

Formula

C28H24ClN3O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CC1=CC=CC(N2C(C3=C(C4=C2C=CC=C4Cl)ON=C3C)=O)=C1)NC5=CC(OC)=C(C(OC)=C5)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (93.64 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8728 mL 9.3640 mL 18.7280 mL
5 mM 0.3746 mL 1.8728 mL 3.7456 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8728 mL 9.3640 mL 18.7280 mL 46.8200 mL
5 mM 0.3746 mL 1.8728 mL 3.7456 mL 9.3640 mL
10 mM 0.1873 mL 0.9364 mL 1.8728 mL 4.6820 mL
15 mM 0.1249 mL 0.6243 mL 1.2485 mL 3.1213 mL
20 mM 0.0936 mL 0.4682 mL 0.9364 mL 2.3410 mL
25 mM 0.0749 mL 0.3746 mL 0.7491 mL 1.8728 mL
30 mM 0.0624 mL 0.3121 mL 0.6243 mL 1.5607 mL
40 mM 0.0468 mL 0.2341 mL 0.4682 mL 1.1705 mL
50 mM 0.0375 mL 0.1873 mL 0.3746 mL 0.9364 mL
60 mM 0.0312 mL 0.1561 mL 0.3121 mL 0.7803 mL
80 mM 0.0234 mL 0.1170 mL 0.2341 mL 0.5852 mL
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LY-402913 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LY-402913334970-65-9LY402913LY 402913OthersHeLa-T5 cellsP-glycoproteinInhibitorinhibitorinhibit

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