2. GPCR/G Protein Neuronal Signaling
  3. Neurotensin Receptor
  4. [Lys8, Lys9]-Neurotensin (8-13)

[Lys8, Lys9]-Neurotensin (8-13)  (Synonyms: JMV438)

Cat. No.: HY-P2544 Purity: 99.97%
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[Lys8, Lys9]-Neurotensin (8-13) (JMV438), a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, with Ki values of 0.33 nM and 0.95 nM for hNTS1 and hNTS2 receptors, respectively.

For research use only. We do not sell to patients.

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[Lys8, Lys9]-Neurotensin (8-13) Chemical Structure

[Lys8, Lys9]-Neurotensin (8-13) Chemical Structure

CAS No. : 139026-64-5

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1 mg USD 55 In-stock
5 mg USD 150 In-stock
10 mg USD 250 In-stock
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Based on 1 publication(s) in Google Scholar

[Lys8, Lys9]-Neurotensin (8-13) Related Antibodies

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Description

[Lys8, Lys9]-Neurotensin (8-13) (JMV438), a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, with Ki values of 0.33 nM and 0.95 nM for hNTS1 and hNTS2 receptors, respectively[1].

Molecular Weight

761.00

Formula

C38H64N8O8
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

KKPYIL
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (131.41 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3141 mL 6.5703 mL 13.1406 mL
5 mM 0.2628 mL 1.3141 mL 2.6281 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.3141 mL 6.5703 mL 13.1406 mL 32.8515 mL
5 mM 0.2628 mL 1.3141 mL 2.6281 mL 6.5703 mL
10 mM 0.1314 mL 0.6570 mL 1.3141 mL 3.2852 mL
15 mM 0.0876 mL 0.4380 mL 0.8760 mL 2.1901 mL
20 mM 0.0657 mL 0.3285 mL 0.6570 mL 1.6426 mL
25 mM 0.0526 mL 0.2628 mL 0.5256 mL 1.3141 mL
30 mM 0.0438 mL 0.2190 mL 0.4380 mL 1.0951 mL
40 mM 0.0329 mL 0.1643 mL 0.3285 mL 0.8213 mL
50 mM 0.0263 mL 0.1314 mL 0.2628 mL 0.6570 mL
60 mM 0.0219 mL 0.1095 mL 0.2190 mL 0.5475 mL
80 mM 0.0164 mL 0.0821 mL 0.1643 mL 0.4106 mL
100 mM 0.0131 mL 0.0657 mL 0.1314 mL 0.3285 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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[Lys8, Lys9]-Neurotensin (8-13) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Lys8, Lys9]-Neurotensin (8-13)139026-64-5JMV438JMV 438JMV-438Neurotensin ReceptorInhibitorinhibitorinhibit

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