1. Anti-infection
  2. Bacterial
  3. Lysicamine

Lysicamine, a natural compound, possesses antibacterial, anticancer and anti-inflammation activity.

For research use only. We do not sell to patients.

Lysicamine Chemical Structure

Lysicamine Chemical Structure

CAS No. : 15444-20-9

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Based on 1 publication(s) in Google Scholar

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Description

Lysicamine, a natural compound, possesses antibacterial, anticancer and anti-inflammation activity[1].

Cellular Effect
Cell Line Type Value Description References
HepG2 IC50
> 40 μM
Compound: 4K
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 35092899]
HepG2 IC50
6.2 μg/mL
Compound: 7
Cytotoxicity against human HepG2 cells by MTT assay
Cytotoxicity against human HepG2 cells by MTT assay
[PMID: 11374955]
HepG2 2.2.15 IC50
2.4 μg/mL
Compound: 7
Cytotoxicity against human HepG2(2.2.15) cells by MTT assay
Cytotoxicity against human HepG2(2.2.15) cells by MTT assay
[PMID: 11374955]
MGC-803 IC50
15.8 μM
Compound: 4K
Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 35092899]
RAW264.7 IC50
6.4 μM
Compound: 9
Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess reagent based assay
Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess reagent based assay
[PMID: 33939429]
SK-OV-3 IC50
12.1 μM
Compound: 4K
Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 35092899]
T-24 IC50
7.3 μM
Compound: 4K
Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 35092899]
WI-38 IC50
6.7 μM
Compound: 4K
Antiproliferative activity against human WI-38 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Antiproliferative activity against human WI-38 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 35092899]
Molecular Weight

291.30

Formula

C18H13NO3

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C2=CC=CC=C2C3=C(OC)C(OC)=CC4=CC=NC1=C43

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Lysicamine
Cat. No.:
HY-122930
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