Mal-C2-Gly3-EDA-PNU-159682

Name: Mal-C2-Gly3-EDA-PNU-159682
Brand: MedChemExpress
SKU: HY-126688
Rating: 4.5 (1 reviews)

Cat. No.: HY-126688 Purity: 93.43%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Mal-C2-Gly3-EDA-PNU-159682, a agent-linker conjugate for ADC, consists a cleavable ADC linker Mal-C2-Gly3-EDA and a potent ADC cytotoxin PNU-159682.

For research use only. We do not sell to patients.

Mal-C2-Gly3-EDA-PNU-159682 Chemical Structure

CAS No. : 2259318-53-9

Size	Price	Stock	Quantity
1 mg	USD 660	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 1495	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 2392	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
Customer Review

Description

Mal-C2-Gly3-EDA-PNU-159682, a agent-linker conjugate for ADC, consists a cleavable ADC linker Mal-C2-Gly3-EDA and a potent ADC cytotoxin PNU-159682.

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

991.95

Formula

C₄₆H₅₃N₇O₁₈

CAS No.

2259318-53-9

Appearance

Solid

Color

Orange to red

SMILES

O=C([C@@]1(O)C[C@H](O[C@H]2C[C@@]3([H])[C@]([C@H](C)O2)([H])O[C@]4([H])[C@@H](OC)OCCN43)C5=C(O)C6=C(C(C7=CC=CC(OC)=C7C6=O)=O)C(O)=C5C1)NCCNC(CNC(CNC(CNC(CCN8C(C=CC8=O)=O)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (100.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0081 mL	5.0406 mL	10.0812 mL
5 mM	0.2016 mL	1.0081 mL	2.0162 mL
10 mM	0.1008 mL	0.5041 mL	1.0081 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 93.43%

Select Batch:

Data Sheet (256 KB) SDS (252 KB)

COA (269 KB) HNMR (450 KB) RP-HPLC (271 KB) MS (68 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0081 mL	5.0406 mL	10.0812 mL	25.2029 mL
	5 mM	0.2016 mL	1.0081 mL	2.0162 mL	5.0406 mL
	10 mM	0.1008 mL	0.5041 mL	1.0081 mL	2.5203 mL
	15 mM	0.0672 mL	0.3360 mL	0.6721 mL	1.6802 mL
	20 mM	0.0504 mL	0.2520 mL	0.5041 mL	1.2601 mL
	25 mM	0.0403 mL	0.2016 mL	0.4032 mL	1.0081 mL
	30 mM	0.0336 mL	0.1680 mL	0.3360 mL	0.8401 mL
	40 mM	0.0252 mL	0.1260 mL	0.2520 mL	0.6301 mL
	50 mM	0.0202 mL	0.1008 mL	0.2016 mL	0.5041 mL
	60 mM	0.0168 mL	0.0840 mL	0.1680 mL	0.4200 mL
	80 mM	0.0126 mL	0.0630 mL	0.1260 mL	0.3150 mL
	100 mM	0.0101 mL	0.0504 mL	0.1008 mL	0.2520 mL