2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Malic acid-d3

Malic acid-d3  (Synonyms: Hydroxybutanedioic acid-d3; E 296-d3)

Cat. No.: HY-Y1311S Purity: 99.89%
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Malic acid-d3 is the deuterium labeled Malic acid. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods[1][2].

For research use only. We do not sell to patients.

Malic acid-d<sub>3</sub> Chemical Structure

Malic acid-d3 Chemical Structure

CAS No. : 104596-63-6

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5 mg USD 280 In-stock
10 mg USD 450 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Malic acid-d3:

Malic acid-d3 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Malic acid-d3 is the deuterium labeled Malic acid. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Malic acid-d3 Related Antibodies
Molecular Weight

137.11

Formula

C4H3D3O5
CAS No.
Unlabeled CAS

6915-15-7
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(O)C([2H])([2H])C([2H])(O)C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (729.34 mM; Need ultrasonic)

DMSO : 100 mg/mL (729.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 100 mg/mL (729.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 100 mg/mL (729.34 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.2934 mL 36.4671 mL 72.9341 mL
5 mM 1.4587 mL 7.2934 mL 14.5868 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO / DMSO / H2O 1 mM 7.2934 mL 36.4671 mL 72.9341 mL 182.3354 mL
5 mM 1.4587 mL 7.2934 mL 14.5868 mL 36.4671 mL
10 mM 0.7293 mL 3.6467 mL 7.2934 mL 18.2335 mL
15 mM 0.4862 mL 2.4311 mL 4.8623 mL 12.1557 mL
20 mM 0.3647 mL 1.8234 mL 3.6467 mL 9.1168 mL
25 mM 0.2917 mL 1.4587 mL 2.9174 mL 7.2934 mL
30 mM 0.2431 mL 1.2156 mL 2.4311 mL 6.0778 mL
40 mM 0.1823 mL 0.9117 mL 1.8234 mL 4.5584 mL
50 mM 0.1459 mL 0.7293 mL 1.4587 mL 3.6467 mL
60 mM 0.1216 mL 0.6078 mL 1.2156 mL 3.0389 mL
80 mM 0.0912 mL 0.4558 mL 0.9117 mL 2.2792 mL
100 mM 0.0729 mL 0.3647 mL 0.7293 mL 1.8234 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Malic acid-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Malic acid-d3104596-63-6Hydroxybutanedioic acid-d3E 296-d3Endogenous MetaboliteInhibitorinhibitorinhibit

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