1. GPCR/G Protein Neuronal Signaling
  2. Somatostatin Receptor
  3. MAT2A-IN-2

MAT2A-IN-2 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-2 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-2 has the potential for the research of cancer diseases (extracted from patent WO2020243376A1, compound 172).

For research use only. We do not sell to patients.

MAT2A-IN-2 Chemical Structure

MAT2A-IN-2 Chemical Structure

CAS No. : 2565671-21-6

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Description

MAT2A-IN-2 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-2 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-2 has the potential for the research of cancer diseases (extracted from patent WO2020243376A1, compound 172)[1].

Molecular Weight

466.42

Formula

C23H17F3N6O2

CAS No.
SMILES

O=C1C(C2=CN3C=CN=C3C=C2)=CC4=C(N1C5=CC=C(C=C5)OC)N=C(NCC(F)(F)F)N=C4

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MAT2A-IN-2
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HY-142929
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