2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. Matuzumab

Matuzumab (EMD 72000) is a humanized anti-EGFR monoclonal antibody that blocks EGFR activation and downstream signaling, inhibits tumor growth.

For research use only. We do not sell to patients.

CAS No. : 339186-68-4

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Based on 1 publication(s) in Google Scholar

Matuzumab Related Antibodies

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EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

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Description

Matuzumab (EMD 72000) is a humanized anti-EGFR monoclonal antibody that blocks EGFR activation and downstream signaling, inhibits tumor growth[1].

Isotype

Human IgG1-nd
Species

Humanized

Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Matuzumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 nd
Biological Activity
  • Immobilized Human EGFR Protein (ECD, His Tag) can bind Matuzumab. The EC50 for this effect is 1.802 ng/mL.
Purity & Documentation
References
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Matuzumab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Matuzumab339186-68-4EMD 72000EMD72000EMD-72000EGFREpidermal growth factor receptorErbB-1HER1humanized anti-EGFR monoclonal antibodytumorInhibitorinhibitorinhibit

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