MC-Val-Cit-PAB-Ispinesib

Cat. No.: HY-160441 Purity: 99.85%: Data Sheet
SDS

COA
Handling Instructions Technical Support

Solubility

In Vivo Dissolution Calculator

MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent inhibitor of Eg5. MC-Val-Cit-PAB-Ispinesib is a click chemistry reagent.

For research use only. We do not sell to patients.

MC-Val-Cit-PAB-Ispinesib Chemical Structure

CAS No. : 1629737-40-1

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent inhibitor of Eg5. MC-Val-Cit-PAB-Ispinesib is a click chemistry reagent^[1].

Molecular Weight

1115.71

Formula

C₅₉H₇₁ClN₁₀O₁₀

CAS No.

1629737-40-1

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=C(C=C1)C)N(CCCNC(OCC2=CC=C(C=C2)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)=O)[C@@H](C(N4CC5=CC=CC=C5)=NC6=CC(Cl)=CC=C6C4=O)C(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

Chloroform : ≥ 100 mg/mL (89.63 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.8963 mL	4.4815 mL	8.9629 mL
5 mM	0.1793 mL	0.8963 mL	1.7926 mL
10 mM	0.0896 mL	0.4481 mL	0.8963 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Purity & Documentation

Purity: 99.85%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (256 KB) HNMR (288 KB) RP-HPLC (258 KB) LCMS (132 KB)

Handling Instructions (2659 KB)

References

[1]. Paul A. Barsanti, et al. Cell proliferation inhibitors and conjugates thereof. WO2014151030. 2014-09-25

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Chloroform	1 mM	0.8963 mL	4.4815 mL	8.9629 mL	22.4073 mL
	5 mM	0.1793 mL	0.8963 mL	1.7926 mL	4.4815 mL
	10 mM	0.0896 mL	0.4481 mL	0.8963 mL	2.2407 mL
	15 mM	0.0598 mL	0.2988 mL	0.5975 mL	1.4938 mL
	20 mM	0.0448 mL	0.2241 mL	0.4481 mL	1.1204 mL
	25 mM	0.0359 mL	0.1793 mL	0.3585 mL	0.8963 mL
	30 mM	0.0299 mL	0.1494 mL	0.2988 mL	0.7469 mL
	40 mM	0.0224 mL	0.1120 mL	0.2241 mL	0.5602 mL
	50 mM	0.0179 mL	0.0896 mL	0.1793 mL	0.4481 mL
	60 mM	0.0149 mL	0.0747 mL	0.1494 mL	0.3735 mL
	80 mM	0.0112 mL	0.0560 mL	0.1120 mL	0.2801 mL