2. Academic Validation
  3. Neobulgarones A approximately F from cultures of Neobulgaria pura, new inhibitors of appressorium formation of Magnaporthe grisea

Neobulgarones A approximately F from cultures of Neobulgaria pura, new inhibitors of appressorium formation of Magnaporthe grisea

  • J Antibiot (Tokyo). 2000 Oct;53(10):1123-9. doi: 10.7164/antibiotics.53.1123.
F Eilbert 1,  H Anke,  O Sterner
Affiliations

Affiliation

  • 1 Institute for Biotechnology and Drug Research, Kaiserslautern, Germany.
PMID: 11132957 DOI: 10.7164/antibiotics.53.1123
Abstract

Six new dimeric anthraquinone derivatives, neobulgarones A (3a), B (3b), C (4a), D (4b), E (5a) and F (5b), were isolated from the mycelia of the ascomycete Neobulgaria pura together with the monomeric carviolin (1) and 1-O-methylemodin (2). All new compounds inhibited the formation of appressoria in germinating conidia of Magnaporthe grisea on inductive (hydrophobic) surface. The compounds exhibited moderate cytotoxic, but no Antifungal, Antibacterial, or phytotoxic activities.

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