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Carviolin is a compound isolated from the mycelia of the ascomycete Neobulgaria pura. Carviolin inhibits the formation of appressoria in germinating conidia of Magnaporthe grisea on inductive (hydrophobic) surface. Carviolin exhibits moderate cytotoxic, but no antifungal, antibacterial, or phytotoxic activities.

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Carviolin Chemical Structure

Carviolin Chemical Structure

CAS No. : 478-35-3

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Based on 1 publication(s) in Google Scholar

Carviolin Related Antibodies

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Description

Carviolin is a compound isolated from the mycelia of the ascomycete Neobulgaria pura. Carviolin inhibits the formation of appressoria in germinating conidia of Magnaporthe grisea on inductive (hydrophobic) surface. Carviolin exhibits moderate cytotoxic, but no antifungal, antibacterial, or phytotoxic activities[1].

Cellular Effect
Cell Line Type Value Description References
Jurkat IC50
> 100 μM
Compound: 9
Cytotoxicity against human Jurkat cells after 24 hrs by MTT assay
Cytotoxicity against human Jurkat cells after 24 hrs by MTT assay
[PMID: 21146414]
K562 IC50
> 100 μM
Compound: 9
Inhibition of NF-kappaB activity in TNFalpha-stimulated human K562 cells after 24 hrs by luciferase reporter gene assay
Inhibition of NF-kappaB activity in TNFalpha-stimulated human K562 cells after 24 hrs by luciferase reporter gene assay
[PMID: 21146414]
U-937 IC50
> 100 μM
Compound: 9
Cytotoxicity against human U937 cells after 24 hrs by MTT assay
Cytotoxicity against human U937 cells after 24 hrs by MTT assay
[PMID: 21146414]
Molecular Weight

300.26

Formula

C16H12O6
CAS No.
SMILES

O=C1C2=C(C=C(CO)C=C2OC)C(C3=CC(O)=CC(O)=C13)=O
Structure Classification
Initial Source

Penicillium dravuni
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Carviolin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Carviolin478-35-3FungalmyceliaascomyceteappressoriacytotoxicconidiaInhibitorinhibitorinhibit

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