1. Academic Validation
  2. Steroidal alkaloid glycosides from tomato (Lycopersicon esculentum)

Steroidal alkaloid glycosides from tomato (Lycopersicon esculentum)

  • J Nat Prod. 2004 Mar;67(3):500-2. doi: 10.1021/np030382x.
Shoji Yahara 1 Noriko Uda Eri Yoshio Emiko Yae
Affiliations

Affiliation

  • 1 Medicinal Plant Garden, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973, Japan. yaharas1@gpo.kumamoto-u.ac.jp
Abstract

Three new steroidal alkaloid glycosides, lycoperosides F-H (1-3), were isolated from tomato fruits (Lycopersicon sculentum) along with lycoperosides A-D, esculeoside A, and rutin. The structures of these glycosides were characterized as the 3-O-beta-lycotetraosides of 23(R)-23-acetoxy-27-hydroxy-27-O-beta-d-glucopyranosyltomatidine (1), (23S,24R)-23-acetoxy-24-O-beta-d-glucopyranosylsoladulcidine-24-ol (2), and 22-isopimpifolidine (3), by means of their spectroscopic data. Also obtained was the new natural product lycoperodine-1 (4).

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