2. Academic Validation
  3. Cucurbitacins as Constituents of Wilbrandia ebracteata

Cucurbitacins as Constituents of Wilbrandia ebracteata

  • Planta Med. 1993 Jun;59(3):272-5. doi: 10.1055/s-2006-959668.
M R Farias 1,  E P Schenkel,  R Mayer,  G Rücker
Affiliations

Affiliation

  • 1 From Farias, M. R. (1991) Thesis, Universität Bonn, Germany. New address: Departamento de Ciencias Farmaceuticas do Centro de Ciencias da Saude da Universidade Federal de Santa Catarina - UFSC, Campus Universitáario, Trindade, 88.049 Florianópolis, SC, Brazil.
PMID: 17235971 DOI: 10.1055/s-2006-959668
Abstract

The methanolic extract from the roots of WILBRANDIA EBRACTEATA afforded, in addition to the known dihydrocucurbitacins B and E, dihydroisocucurbitacin B, Cucurbitacins B, D, E, G, H, P, and 22-deoxycucurbi-tacin D, four new compounds whose structures were elucidated as (20 R,24xi)-3)3beta,16alpha,20)24,25-pentahydroxy-10alpha-cucurbit-5-ene-2,11,22-trione (3- EPI-isocucurbitacin G) ( 8), (20 R,22xi)-2beta16a,20,22,25-pentahydroxy-10alpha-cucurbita-5,23 T-diene-3,11-dione ( 13), (20 R)-25-acetoxy-3,16alpha,20-trihydroxy-30- NOR-2-(beta- D-glucopyranosyloxy)-1,2,3,4,5,10-dehydrocucurbit-6-ene-11,22-dione ( 14), and dihydroisocucurbitacin B-3-glucoside ( 16).

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