2. Academic Validation
  3. Synthesis and nematocidal activities of jietacin A and its analogs

Synthesis and nematocidal activities of jietacin A and its analogs

  • J Antibiot (Tokyo). 1991 Jul;44(7):774-84. doi: 10.7164/antibiotics.44.774.
K Tsuzuki 1,  F S Yan,  K Otoguro,  S Omura
Affiliations

Affiliation

  • 1 Research Center for Biological Function, Kitasato Institute, Tokyo, Japan.
PMID: 1880067 DOI: 10.7164/antibiotics.44.774
Abstract

Simple, efficient syntheses of jietacin A, a nematocidal Antibiotic, and its analogs have been developed in order to study structure-activity relationships. A series of alpha,beta-unsaturated azoxy compounds was prepared from phenylselenomethyl azoxy compounds as key intermediates and its nematocidal activity was determined.

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