2. Academic Validation
  3. Bromotyrosine alkaloids from the Australian marine sponge Pseudoceratina verrucosa

Bromotyrosine alkaloids from the Australian marine sponge Pseudoceratina verrucosa

  • J Nat Prod. 2013 Apr 26;76(4):516-23. doi: 10.1021/np300648d.
Trong D Tran 1,  Ngoc B Pham,  Gregory Fechner,  John N A Hooper,  Ronald J Quinn
Affiliations

Affiliation

  • 1 Eskitis Institute, Griffith University, Brisbane, Queensland 4111, Australia.
PMID: 23489291 DOI: 10.1021/np300648d
Abstract

Two new bromotyrosine Alkaloids, pseudoceralidinone A (1) and aplysamine 7 (2), along with three known compounds were isolated from the Australian Sponge Pseudoceratina verrucosa. Their structures were characterized by NMR and MS data and the synthetic route. Their cytotoxicity was evaluated against Cancer cell lines (HeLa and PC3) and a noncancer cell line (NFF).

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