Elucidation of the physiology of non-replicating, drug tolerant Mycobacterium tuberculosis with the aid of the small molecule probe ML338

Partha P. Nag ¹, Sarah Schmidt Grant ² ³ ⁴ ⁵, Timothy A. Lewis ¹, Katie Gordon ², Tomohiko Kawate ² ⁴ ⁵, Noriaki Iwase ², E. Lucile White ⁶, Clinton Maddox ⁶, Ntsang Miranda Nebane ⁶, Nichole A. Tower ⁶, Sara McKellip ⁶, Melinda I. Sosa ⁶, Lynn Rasmussen ⁶, Carrie M. Mosher ¹, Travis Anthoine ¹, Stephen Johnston ¹, Sivaraman Dandapani ¹, José Perez ¹, Benito Munoz ¹, Michelle Palmer ¹, Stuart L. Schreiber ¹, Deborah T. Hung ² ³ ⁴ ⁵

Affiliations

1 The Broad Institute Probe Development Center, Cambridge, MA
2 Broad Institute of MIT and Harvard, Cambridge, MA 02142
3 Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02114
4 Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114
5 Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115
6 Southern Research Specialized Biocontainment Screening Center, Southern Research Institute, Birmingham, AL 35205

PMID: 24260778

Products

Cat. No.

Product Name

Description

Target

Research Area
HY-136348

ML338

Anti-Tuberculosis Agent

Bacterial

Infection

Name
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